Diisononyl phthalate (DINP)
- Status: Diisononyl phthalate (DINP) is in step 1 at this time.
IRIS Toxicological Review of Diisononyl Phthalate (Dinp) (Preliminary Assessment Materials)
- Draft literature search strategies
- The approach for identifying studies
- The screening process for selecting pertinent studies
- The resulting list of pertinent studies
- Preliminary evidence tables
- The process for selecting studies to include in evidence tables
- The quality of the studies in the evidence tables
U.S. EPA. IRIS Toxicological Review of Diisononyl Phthalate (Dinp) (Preliminary Assessment Materials). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-14/242, 2014.
Xabier Arzuaga, Ph: 202-564-1361, Email: firstname.lastname@example.org
DINP is used in the production of plastics to increase flexibility and is commonly present in products such as toys, vinyl swimming pools, vinyl containing furniture and clothes, flooring, gloves, drinking straws, garden hoses and sealants used in food packaging. Most DINP is used in PVC products, with less than 10% used in non-PVC products such as different types of rubber, inks, pigments, paints, lacquers, adhesives, and sealants.
The use of di-2-ethylhexyl phthalate (DEHP) has largely been replaced by DINP, though not in medical products. In 2008, the Consumer Product Safety Improvement Act (CPSIA) placed an interim ban on DINP in children’s toys and certain child care articles at concentrations greater than 0.1 percent. The Chronic Hazard Advisory Panel (CHAP) recommended that the interim ban on DINP be made permanent in children’s toys and child care products at level greater than 0.1%.
|Aug 2014||EPA released Preliminary Assessment Materials (draft literature searches and associated search strategies, evidence tables and exposure response arrays) in anticipation for discussion at an upcoming IRIS Public Science Meeting.|
|Oct 2014||EPA discussed DINP at the October 2014 IRIS public science meeting.|
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
- (131 pp, 2 MB, about PDF)
Comments on the assessment may be submitted and reviewed using the Docket ID EPA-HQ-ORD-2014-0637