Pentachlorophenol
CASRN 87-86-5
- Toxicological Review (PDF) (288 pp, 2.23 M)
- IRIS Summary (PDF) (27 pp, 261 K)
IRIS Toxicological Review of Pentachlorophenol (Final Report)
Overview
Citation
U.S. EPA. IRIS Toxicological Review of Pentachlorophenol (Final Report). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-09/004F, 2010.
Background
Pentachlorophenol is a wood preservative used to prevent decay from fungal organisms and insect damage. Use by the public was restricted in 1984, and application was limited to industrial areas. It has been reported in food, surface water, groundwater, rainwater, and soil. People who work or reside in close proximity to wood treatment facilities, treated lumber, or hazardous waste sites are likely exposed.
This assessment contains a revised oral reference dose (RfD) for chronic noncancer health effects as well as a revised oral cancer risk estimate.
History/Chronology
| Date | Description |
|---|---|
| Jan 1987 | EPA posted the pentachlorophenol assessment on the IRIS database (RfD only). |
| Mar 1991 | EPA posted the carcinogenicity assessment for oral exposure to pentachlorophenol on the IRIS database. |
| May 2009 | EPA released the external review draft report for public review and comment. |
| Jun 2009 | EPA announced a public listening session for the draft review report. [Fedral Register Notice Jun 9, 2009] |
| Jun 2009 | EPA announced the external peer review meeting to be held August 4, 2009 in Arlington, VA. [Federal Register Notice Jun 29, 2009] |
| Oct 2009 | EPA released the comments from the external review workshop and public comment period. |
| Jul 2010 | EPA hosted an interagency science discussion on the review of the draft Toxicological Review of Pentachlorophenol . |
| Sep 2010 | EPA released the final toxicological report and IRIS Summary for Pentachlorophenol, and the interagency science discussion review draft with comments. |
Download(s)
This document has been reviewed in accordance with U.S. Environmental Protection Agency policy and approved for publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.
- IRIS Toxicological Review of Pentachlorophenol (PDF) (288 pp, 2 MB, about PDF)
- IRIS Summary for Pentachlorophenol (PDF) (26 pp, 221 KB, about PDF)
If you have a disability and the format of any material on our web pages interferes with your ability to access the information, please reach out to us using the Contact us about IRIS form for assistance. To enable us to respond in a manner most helpful to you, please indicate the nature of the accessibility problem, the web address of the requested material, your preferred format in which you want to receive the material (electronic format (ASCII, etc.), standard print, large print, etc.), and your contact information.