CASRN 75-09-2

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IRIS Toxicological Review of Dichloromethane (Methylene Chloride) (Final Report)


EPA has finalized the Toxicological Review of Dichloromethane (Methylene Chloride): In support of the Integrated Risk Information System (IRIS). Now final, this assessment may be used by EPA’s program and regional offices to inform decisions to protect human health. This document presents background information and justification for the Intergrated Risk Information System (IRIS) Summary of the hazard and dose-response assessment of dichloromethane. IRIS Summaries may include oral reference dose (RfD) and inhalation reference concentration (RfC) values for chronic and other exposure durations, and a carcinogencity assessment.


U.S. EPA. IRIS Toxicological Review of Dichloromethane (Methylene Chloride) (Final Report). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-10/003F, 2011.

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This document has been reviewed in accordance with U.S. Environmental Protection Agency policy and approved for publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.

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