IRIS Toxicological Review of Urea (Interagency Science Consultation Draft)
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U.S. EPA. IRIS Toxicological Review of Urea (Interagency Science Consultation Draft) . U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-10/005C, 2010.
The draft Toxicological Review of Urea provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to Urea. Urea, also known as carbamide, is an endogenous product of protein and amino acid catabolism. It can also be produced synthetically by combining ammonia, carbon monoxide, and sulfur in methanol. Urea is utilized in diesel selective catalyst reduction, in fertilizers and animal feed, plastics, flame-proofing agents, adhesives, flavoring agents and consumer goods such as liquid soaps, detergents and household cleaning products.
|Jun 2010||EPA initiated the interagency science consultation on the draft Toxicological Review of Urea.|
|Sep 2010||EPA released the External Review Draft for public review and comment. EPA also announced a public listening session to be held on Nov 16, 2010. [Federal Register September 28, 2010]|
Following external peer review the assessment will be revised taking into consideration external peer review and public comments. It will then undergo a final EPA internal review and a review by other federal agencies and White House offices, followed by posting to the IRIS Web site.
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.