Hydrogen Cyanide and Cyanide Salts
- Toxicological Review (PDF) (153 pp, 905 K)
- IRIS Summary (PDF) (27 pp, 243 K)
IRIS Toxicological Review of Hydrogen Cyanide (External Review Draft)
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U.S. EPA. IRIS Toxicological Review of Hydrogen Cyanide (External Review Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-08/016, 2009.
The draft Toxicological Review of Hydrogen Cyanide and Cyanide Salts provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to hydrogen cyanide and cyanide salts. Cyanide compounds are used in a number of industrial processes including mining, electroplating, metallurgy, chemical manufacturing, and photography because these compounds can form stable complexes with a range of metals. Hydrogen cyanide is also a component of tobacco smoke, vehicle exhaust, and is produced by the burning of some plastics. Cyanide salts, such as potassium and sodium cyanide, are also used as rodenticides.
|Jan 1987||EPA posted an assessment for cyanide salts (RfD only).|
|Sep 1994||EPA posted an assessment for hydrogen cyanide (RfC only).|
|Jun 2004||The IRIS reassessment of hydrogen cyanide was initiated in 2004.|
|Sep 2009||EPA released an external review draft of the assessment for public review and comment.|
|Oct 2009||EPA announced a public listening session that was held on October 27, 2009 in a September 23, 2009 Federal Register Notice.|
|Nov 2009||EPA announced the details of an external peer review workshop to be held on December 14, 2009 in a November 10, 2009 Federal Register Notice.|
|Jan 2010||EPA released the comments from the public comment period and external review workshop.|
Following the External Peer Review, the final assessment will be published on the IRIS database.
Comments on the assessment may be submitted and reviewed using the e-Government Regulations.gov Web site. From the site, select “Environmental Protection Agency” and the keyword “EPA-HQ-ORD-2009-0245” (for the docket ID) to comment on this report.
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