Cerium Oxide and Cerium Compounds
CASRN 1306-38-3
- Toxicological Review (PDF) (118 pp, 720 K)
- IRIS Summary (PDF) (19 pp, 205 K)
IRIS Toxicological Review of Cerium Oxide and Cerium Compounds (External Review Draft)
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Overview
Citation
U.S. EPA, AND M. GEHLHAUS. IRIS Toxicological Review of Cerium Oxide and Cerium Compounds (External Review Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-08/002A.
Background
The draft Toxicological Review of cerium oxide and cerium compounds provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to cerium oxide and cerium compounds. Cerium oxide is a polishing agent for glass mirrors, plate glass, television tubes, ophthalmic lenses, and precision optics, and is also used in emission control systems in gasoline engines and as a diesel fuel-born catalyst to reduce particulate matter emissions. Cerium is most heavily used in the form of mischmetal, a commercial mixture of metallic light lanthanides, for metallurgical purposes.
This assessment contains the derivation of a chronic reference concentration and a cancer characterization.
History/Chronology
| Date | Description |
|---|---|
| 2005 | EPA began reviewing the Tox Assessment of cerium oxide and cerium compounds. |
| May 2007 | EPA announces the external peer review panel meeting in a May 6, 2007 Federal Register Notice. |
| May 2008 | EPA releases the draft document for an external peer review. |
| Sep 2009 | EPA released the Final Toxicological Review (PDF) (118 pp, 703K) and accompanying Summary for Cerium Oxides to the IRIS Web site. |
Status
Following External Peer Review, the final assessment is scheduled to be posted to the IRIS database.
Additional Information
Comments on the assessment may be submitted and reviewed using the e-Government Regulations.gov Web site. From the site, select Environmental Protection Agency and the key word EPA- HQ-ORD-2008-0111 (for the docket ID).
Download(s)
- Toxicological Review of Cerium Oxide (External Review Draft) (PDF) (88 pp, 460 KB, about PDF)
- Charge to External Peer Reviewers (PDF) (3 pp, 21 KB, about PDF)
- Listening Session Announcement
- Consolidated Comments from the External Peer Review (Final) (PDF) (42 pp, 327 KB, about PDF)
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Related Link(s)
- External Peer Review of Bio-Research Labs (1994) Final Report (PDF) (23 pp, 176 KB, about PDF)
- Prinicipal Study: Bio-Research Labs 1994 (PDF) (1360 pp, 25 MB, about PDF)