Cerium Oxide and Cerium Compounds
IRIS Toxicological Review of Cerium Oxide and Cerium Compounds (External Review Draft)
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U.S. EPA, AND M. GEHLHAUS. IRIS Toxicological Review of Cerium Oxide and Cerium Compounds (External Review Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-08/002A.
The draft Toxicological Review of cerium oxide and cerium compounds provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to cerium oxide and cerium compounds. Cerium oxide is a polishing agent for glass mirrors, plate glass, television tubes, ophthalmic lenses, and precision optics, and is also used in emission control systems in gasoline engines and as a diesel fuel-born catalyst to reduce particulate matter emissions. Cerium is most heavily used in the form of mischmetal, a commercial mixture of metallic light lanthanides, for metallurgical purposes.
This assessment contains the derivation of a chronic reference concentration and a cancer characterization.
|2005||EPA began reviewing the Tox Assessment of cerium oxide and cerium compounds.|
|May 2007||EPA announces the external peer review panel meeting in a May 6, 2007 Federal Register Notice.|
|May 2008||EPA releases the draft document for an external peer review.|
|Sep 2009||EPA released the Final Toxicological Review (PDF) (118 pp, 703K) and accompanying Summary for Cerium Oxides to the IRIS Web site.|
Following External Peer Review, the final assessment is scheduled to be posted to the IRIS database.
Comments on the assessment may be submitted and reviewed using the e-Government Regulations.gov Web site. From the site, select Environmental Protection Agency and the key word EPA- HQ-ORD-2008-0111 (for the docket ID).