IRIS

IRIS Assessments

This page provides a list of final IRIS assessments in alphabetical order by chemical name.

  Chemical Name CASRN Last Significant Revision* IRIS Summary Tox Review/
Support Document
Literature Screening Review Critical Effect Systems Tumor Site
1 Acenaphthene 83-32-9 19901101Nov-01-1990 IRIS Summary for Acenaphthene (PDF 7 pp, 89 K)  Not Available  No
Hepatic
None
2 Acenaphthylene 208-96-8 19910101Jan-01-1991 IRIS Summary for Acenaphthylene (PDF 6 pp, 82 K)  Not Available  No
None
None
3 Acetaldehyde 75-07-0 19911001Oct-01-1991 IRIS Summary for Acetaldehyde (PDF 20 pp, 147 K)  Not Available  No
Nervous
Respiratory
Respiratory
4 Acetone 67-64-1 20030731Jul-31-2003 IRIS Summary for Acetone (PDF 26 pp, 0.23 M) Toxicological Review for Acetone (PDF 85 pp, 1.19 M)  No
Urinary
None
5 Acetonitrile 75-05-8 19990303Mar-03-1999 IRIS Summary for Acetonitrile (PDF 23 pp, 165 K) Toxicological Review for Acetonitrile (PDF 35 pp, 144 K)  No
None
None
6 Acetophenone 98-86-2 19910201Feb-01-1991 IRIS Summary for Acetophenone (PDF 9 pp, 98 K)  Not Available  Yes
None
None
7 Acetyl chloride 75-36-5 19910301Mar-01-1991 IRIS Summary for Acetyl chloride (PDF 5 pp, 87 K)  Not Available  No
None
None
8 Acrolein 107-02-8 20030603Jun-03-2003 IRIS Summary for Acrolein (PDF 25 pp, 176 K) Toxicological Review for Acrolein (PDF 106 pp, 332 K)  No
Respiratory
None
9 Acrylamide 79-06-1 20100322Mar-22-2010 IRIS Summary for Acrylamide (PDF 34 pp, 0.32 M) Toxicological Review for Acrylamide (PDF 459 pp, 4.84 M)  No
Nervous
Endocrine
Reproductive
10 Acrylic acid 79-10-7 19940401Apr-01-1994 IRIS Summary for Acrylic acid (PDF 23 pp, 157 K)  Not Available  Yes
Developmental
Nervous
Respiratory
None
11 Acrylonitrile 107-13-1 19911101Nov-01-1991 IRIS Summary for Acrylonitrile (PDF 23 pp, 162 K)  Not Available  Yes
Respiratory
Gastrointestinal
Nervous
Respiratory
12 Adiponitrile 111-69-3 19910201Feb-01-1991 IRIS Summary for Adiponitrile (PDF 6 pp, 89 K)  Not Available  Yes
None
None
13 Aldicarb sulfone 1646-88-4 19931101Nov-01-1993 IRIS Summary for Aldicarb sulfone (PDF 10 pp, 102 K)  Not Available  Yes
Nervous
None
14 Aldrin 309-00-2 19870930Sep-30-1987 IRIS Summary for Aldrin (PDF 14 pp, 121 K)  Not Available  Yes
Hepatic
Hepatic
15 Allyl alcohol 107-18-6 19870131Jan-31-1987 IRIS Summary for Allyl alcohol (PDF 7 pp, 90 K)  Not Available  Yes
Hepatic
Urinary
None
16 Allyl chloride 107-05-1 19911201Dec-01-1991 IRIS Summary for Allyl chloride (PDF 13 pp, 139 K)  Not Available  Yes
Nervous
None
17 Ammonia 7664-41-7 20160920Sep-20-2016 IRIS Summary for Ammonia (PDF 10 pp, 0.31 M) Toxicological Review for Ammonia (PDF 99 pp, 1.00 M)
Ammonia Support Documents
 Yes
Respiratory
None
18 Ammonium acetate 631-61-8 19910301Mar-01-1991 IRIS Summary for Ammonium acetate (PDF 5 pp, 86 K)  Not Available  No
None
None
19 Ammonium methacrylate 16325-47-6 19910301Mar-01-1991 IRIS Summary for Ammonium methacrylate (PDF 5 pp, 87 K)  Not Available  No
None
None
20 Ammonium sulfamate 7773-06-0 19890101Jan-01-1989 IRIS Summary for Ammonium sulfamate (PDF 7 pp, 89 K)  Not Available  Yes
None
None
21 Aniline 62-53-3 19901101Nov-01-1990 IRIS Summary for Aniline (PDF 19 pp, 139 K)  Not Available  Yes
Hematologic
Immune
22 ortho-Anisidine 90-04-0 19911001Oct-01-1991 IRIS Summary for ortho-Anisidine (PDF 4 pp, 83 K)  Not Available  Yes
None
None
23 Anthracene 120-12-7 19910101Jan-01-1991 IRIS Summary for Anthracene (PDF 13 pp, 114 K)  Not Available  No
None
None
24 Antimony 7440-36-0 19870131Jan-31-1987 IRIS Summary for Antimony (PDF 8 pp, 95 K)  Not Available  Yes
Hematologic
None
25 Antimony trioxide 1309-64-4 19950901Sep-01-1995 IRIS Summary for Antimony trioxide (PDF 21 pp, 158 K)  Not Available  Yes
Respiratory
None
26 Aramite 140-57-8 19910601Jun-01-1991 IRIS Summary for Aramite (PDF 14 pp, 125 K)  Not Available  Yes
None
Hepatic
27 Aroclor 1016 12674-11-2 19930101Jan-01-1993 IRIS Summary for Aroclor 1016 (PDF 19 pp, 145 K)  Not Available  No
Developmental
None
28 Aroclor 1248 12672-29-6 19940401Apr-01-1994 IRIS Summary for Aroclor 1248 (PDF 7 pp, 88 K)  Not Available  No
None
None
29 Aroclor 1254 11097-69-1 19941001Oct-01-1994 IRIS Summary for Aroclor 1254 (PDF 26 pp, 167 K)  Not Available  No
Dermal
Immune
Ocular
None
30 Arsenic, inorganic 7440-38-2 19950601Jun-01-1995 IRIS Summary for Arsenic, inorganic (PDF 29 pp, 186 K)  Not Available Arsenic, inorganic Support Documents  Yes
Cardiovascular
Dermal
Dermal
Respiratory
31 Arsine 7784-42-1 19940301Mar-01-1994 IRIS Summary for Arsine (PDF 17 pp, 139 K)  Not Available  Yes
Hematologic
Immune
None
32 Asbestos 1332-21-4 19880926Sep-26-1988 IRIS Summary for Asbestos (PDF 15 pp, 129 K)  Not Available  No
None
Respiratory
33 Azobenzene 103-33-3 19880907Sep-07-1988 IRIS Summary for Azobenzene (PDF 9 pp, 97 K)  Not Available  Yes
None
None
34 Barium and Compounds 7440-39-3 20050711Jul-11-2005 IRIS Summary for Barium and Compounds (PDF 34 pp, 208 K) Toxicological Review for Barium and Compounds (PDF 88 pp, 325 K)  Yes
Urinary
None
35 Barium cyanide 542-62-1 19910301Mar-01-1991 IRIS Summary for Barium cyanide (PDF 4 pp, 77 K)  Not Available  No
None
None
36 Benz[a]anthracene 56-55-3 19901201Dec-01-1990 IRIS Summary for Benz[a]anthracene (PDF 12 pp, 114 K)  Not Available  No
None
None
37 Benzaldehyde 100-52-7 19880907Sep-07-1988 IRIS Summary for Benzaldehyde (PDF 6 pp, 86 K)  Not Available  Yes
Gastrointestinal
Urinary
None
38 Benzene 71-43-2 20030417Apr-17-2003 IRIS Summary for Benzene (PDF 45 pp, 0.26 M) Noncancer Effects Toxicological Review for Benzene (PDF 180 pp, 1.59 M)
Benzene Support Documents
 No
Immune
Hematologic
39 Benzidine 92-87-5 19910701Jul-01-1991 IRIS Summary for Benzidine (PDF 16 pp, 129 K)  Not Available  Yes
Hepatic
Nervous
Urinary
40 Benzo[a]pyrene (BaP) 50-32-8 20170119Jan-19-2017 IRIS Summary for Benzo[a]pyrene (BaP) (PDF 9 pp, 0.67 M) Toxicological Review for Benzo[a]pyrene (BaP) (PDF 234 pp, 4.67 M)
Benzo[a]pyrene (BaP) Support Documents
 No
Developmental
Immune
Reproductive
Gastrointestinal
Respiratory
41 Benzo[b]fluoranthene 205-99-2 19901201Dec-01-1990 IRIS Summary for Benzo[b]fluoranthene (PDF 8 pp, 94 K)  Not Available  No
None
None
42 Benzo[g,h,i]perylene 191-24-2 19901201Dec-01-1990 IRIS Summary for Benzo[g,h,i]perylene (PDF 8 pp, 98 K)  Not Available  No
None
None
43 Benzo[k]fluoranthene 207-08-9 19901101Nov-01-1990 IRIS Summary for Benzo[k]fluoranthene (PDF 8 pp, 97 K)  Not Available  No
None
None
44 Benzoic acid 65-85-0 19890801Aug-01-1989 IRIS Summary for Benzoic acid (PDF 11 pp, 108 K)  Not Available  Yes
None
None
45 Benzotrichloride 98-07-7 19900701Jul-01-1990 IRIS Summary for Benzotrichloride (PDF 14 pp, 119 K)  Not Available  No
None
Respiratory
46 Benzyl chloride 100-44-7 19920101Jan-01-1992 IRIS Summary for Benzyl chloride (PDF 13 pp, 118 K)  Not Available  Yes
None
Endocrine
47 Beryllium and compounds 7440-41-7 19980403Apr-03-1998 IRIS Summary for Beryllium and compounds (PDF 51 pp, 284 K) Toxicological Review for Beryllium and compounds (PDF 94 pp, 320 K)  Yes
Gastrointestinal
Immune
Respiratory
Respiratory
48 Biphenyl 92-52-4 20130827Aug-27-2013 IRIS Summary for Biphenyl (PDF 12 pp, 0.11 M) Toxicological Review for Biphenyl (PDF 225 pp, 4.82 M)  Yes
Urinary
Hepatic
49 Bis(2-chloro-1-methylethyl) ether 108-60-1 19891001Oct-01-1989 IRIS Summary for Bis(2-chloro-1-methylethyl) ether (PDF 7 pp, 91 K)  Not Available  Yes
Hematologic
None
50 Bis(2-chloroethoxy)methane 111-91-1 19910301Mar-01-1991 IRIS Summary for Bis(2-chloroethoxy)methane (PDF 5 pp, 88 K)  Not Available  Yes
None
None
51 Bis(chloroethyl)ether (BCEE) 111-44-4 19911001Oct-01-1991 IRIS Summary for Bis(chloroethyl)ether (BCEE) (PDF 10 pp, 104 K)  Not Available  Yes
None
Hepatic
52 Bis(chloromethyl)ether (BCME) 542-88-1 19910701Jul-01-1991 IRIS Summary for Bis(chloromethyl)ether (BCME) (PDF 12 pp, 113 K)  Not Available  Yes
None
Respiratory
53 Bisphenol A. 80-05-7 19880926Sep-26-1988 IRIS Summary for Bisphenol A. (PDF 8 pp, 93 K)  Not Available  Yes
None
None
54 Boron and Compounds 7440-42-8 20040805Aug-05-2004 IRIS Summary for Boron and Compounds (PDF 30 pp, 193 K) Toxicological Review for Boron and Compounds (PDF 144 pp, 864 K)  No
Developmental
None
55 Bromate 15541-45-4 20010606Jun-06-2001 IRIS Summary for Bromate (PDF 27 pp, 186 K) Toxicological Review for Bromate (PDF 58 pp, 261 K)  No
Urinary
Endocrine
Reproductive
Urinary
56 Brominated dibenzofurans 19901201Dec-01-1990 IRIS Summary for Brominated dibenzofurans (PDF 5 pp, 81 K)  Not Available  No
None
None
57 Bromobenzene 108-86-1 20090930Sep-30-2009 IRIS Summary for Bromobenzene (PDF 27 pp, 243 K) Toxicological Review for Bromobenzene (PDF 123 pp, 786 K)  No
Hepatic
None
58 Bromochloromethane 74-97-5 19910301Mar-01-1991 IRIS Summary for Bromochloromethane (PDF 6 pp, 93 K)  Not Available  No
None
None
59 Bromodichloromethane 75-27-4 19930201Feb-01-1993 IRIS Summary for Bromodichloromethane (PDF 18 pp, 135 K)  Not Available  Yes
Urinary
Urinary
60 p-Bromodiphenyl ether 101-55-3 19900801Aug-01-1990 IRIS Summary for p-Bromodiphenyl ether (PDF 6 pp, 91 K)  Not Available  No
None
None
61 Bromoform 75-25-2 19931201Dec-01-1993 IRIS Summary for Bromoform (PDF 23 pp, 152 K)  Not Available  Yes
Hepatic
Gastrointestinal
62 Bromomethane 74-83-9 19920401Apr-01-1992 IRIS Summary for Bromomethane (PDF 29 pp, 184 K)  Not Available  Yes
Gastrointestinal
Nervous
Respiratory
None
63 Bromotrichloromethane 75-62-7 19910301Mar-01-1991 IRIS Summary for Bromotrichloromethane (PDF 6 pp, 89 K)  Not Available  Yes
None
None
64 1,3-Butadiene 106-99-0 20021105Nov-05-2002 IRIS Summary for 1,3-Butadiene (PDF 27 pp, 0.19 M)  Not Available 1,3-Butadiene Support Documents  No
Reproductive
Hematologic
65 n-Butanol 71-36-3 19910301Mar-01-1991 IRIS Summary for n-Butanol (PDF 10 pp, 100 K)  Not Available  Yes
Nervous
None
66 Butyl benzyl phthalate (BBP) 85-68-7 19890901Sep-01-1989 IRIS Summary for Butyl benzyl phthalate (BBP) (PDF 12 pp, 111 K)  Not Available  Yes
Hepatic
None
67 t-Butylchloride 507-20-0 19900401Apr-01-1990 IRIS Summary for t-Butylchloride (PDF 6 pp, 86 K)  Not Available  No
None
None
68 Butylphthalyl butylglycolate (BPBG) 85-70-1 19870301Mar-01-1987 IRIS Summary for Butylphthalyl butylglycolate (BPBG) (PDF 6 pp, 86 K)  Not Available  No
None
None
69 Cadmium 7440-43-9 19891001Oct-01-1989 IRIS Summary for Cadmium (PDF 13 pp, 118 K)  Not Available  No
Urinary
Respiratory
70 Calcium cyanide 592-01-8 20100928Sep-28-2010 IRIS Summary for Calcium cyanide (PDF 27 pp, 243 K) Toxicological Review for Calcium cyanide (PDF 153 pp, 905 K)  Yes
Reproductive
None
71 Caprolactam 105-60-2 19940901Sep-01-1994 IRIS Summary for Caprolactam (PDF 17 pp, 134 K)  Not Available  Yes
Developmental
None
72 Captafol 2425-06-1 19870930Sep-30-1987 IRIS Summary for Captafol (PDF 7 pp, 87 K)  Not Available  Yes
Urinary
None
73 Captan 133-06-2 19890301Mar-01-1989 IRIS Summary for Captan (PDF 9 pp, 97 K)  Not Available  No
None
None
74 Carbaryl 63-25-2 19911101Nov-01-1991 IRIS Summary for Carbaryl (PDF 8 pp, 95 K)  Not Available  Yes
Hepatic
Urinary
None
75 Carbon disulfide 75-15-0 19950801Aug-01-1995 IRIS Summary for Carbon disulfide (PDF 30 pp, 185 K)  Not Available  Yes
Developmental
Nervous
None
76 Carbon tetrachloride 56-23-5 20100331Mar-31-2010 IRIS Summary for Carbon tetrachloride (PDF 20 pp, 0.36 M) Toxicological Review for Carbon tetrachloride (PDF 473 pp, 3.04 M)  No
Hepatic
Endocrine
Hepatic
77 Carbonyl sulfide 463-58-1 19911101Nov-01-1991 IRIS Summary for Carbonyl sulfide (PDF 4 pp, 82 K)  Not Available  Yes
None
None
78 Carbosulfan 55285-14-8 19870131Jan-31-1987 IRIS Summary for Carbosulfan (PDF 7 pp, 87 K)  Not Available  Yes
None
None
79 Cerium Oxide and Cerium Compounds 1306-38-3 20090929Sep-29-2009 IRIS Summary for Cerium Oxide and Cerium Compounds (PDF 19 pp, 205 K) Toxicological Review for Cerium Oxide and Cerium Compounds (PDF 118 pp, 720 K)  No
Respiratory
None
80 Chloral hydrate 302-17-0 20000915Sep-15-2000 IRIS Summary for Chloral hydrate (PDF 39 pp, 220 K) Toxicological Review for Chloral hydrate (PDF 69 pp, 148 K)  Yes
Gastrointestinal
Nervous
None
81 Chloramben 133-90-4 19870131Jan-31-1987 IRIS Summary for Chloramben (PDF 7 pp, 89 K)  Not Available  Yes
Hepatic
None
82 Chlordane (Technical) 12789-03-6 19980207Feb-07-1998 IRIS Summary for Chlordane (Technical) (PDF 46 pp, 262 K) Toxicological Review for Chlordane (Technical) (PDF 73 pp, 228 K)  Yes
Hepatic
Hepatic
83 Chlordecone (Kepone) 143-50-0 20090922Sep-22-2009 IRIS Summary for Chlordecone (Kepone) (PDF 24 pp, 0.23 M) Toxicological Review for Chlordecone (Kepone) (PDF 183 pp, 1.03 M)  No
Urinary
Hepatic
84 Chlorine 7782-50-5 19940601Jun-01-1994 IRIS Summary for Chlorine (PDF 14 pp, 120 K)  Not Available  Yes
None
None
85 Chlorine cyanide 506-77-4 19870131Jan-31-1987 IRIS Summary for Chlorine cyanide (PDF 8 pp, 93 K)  Not Available  No
Endocrine
Nervous
None
86 Chlorine dioxide 10049-04-4 20001011Oct-11-2000 IRIS Summary for Chlorine dioxide (PDF 25 pp, 177 K) Toxicological Review for Chlorine dioxide (PDF 56 pp, 144 K)  Yes
Cardiovascular
Developmental
Nervous
Respiratory
None
87 Chlorite (sodium salt) 7758-19-2 20001011Oct-11-2000 IRIS Summary for Chlorite (sodium salt) (PDF 19 pp, 143 K) Toxicological Review for Chlorite (sodium salt) (PDF 56 pp, 144 K)  No
Developmental
Nervous
None
88 1-Chloro-1,1-difluoroethane 75-68-3 19950701Jul-01-1995 IRIS Summary for 1-Chloro-1,1-difluoroethane (PDF 10 pp, 110 K)  Not Available  No
None
None
89 2-Chloroacetophenone 532-27-4 19911001Oct-01-1991 IRIS Summary for 2-Chloroacetophenone (PDF 12 pp, 118 K)  Not Available  Yes
Respiratory
None
90 p-Chloroaniline 106-47-8 19880822Aug-22-1988 IRIS Summary for p-Chloroaniline (PDF 6 pp, 86 K)  Not Available  Yes
Immune
None
91 Chlorobenzene 108-90-7 19901101Nov-01-1990 IRIS Summary for Chlorobenzene (PDF 13 pp, 114 K)  Not Available  Yes
Hepatic
None
92 Chlorobenzilate 510-15-6 19891201Dec-01-1989 IRIS Summary for Chlorobenzilate (PDF 7 pp, 90 K)  Not Available  Yes
Nervous
None
93 1-Chlorobutane 109-69-3 19900401Apr-01-1990 IRIS Summary for 1-Chlorobutane (PDF 9 pp, 95 K)  Not Available  No
None
None
94 2-Chlorobutane 78-86-4 19900401Apr-01-1990 IRIS Summary for 2-Chlorobutane (PDF 6 pp, 85 K)  Not Available  No
None
None
95 Chlorocyclopentadiene 41851-50-7 19900301Mar-01-1990 IRIS Summary for Chlorocyclopentadiene (PDF 5 pp, 80 K)  Not Available  No
None
None
96 Chlorodifluoromethane 75-45-6 19931101Nov-01-1993 IRIS Summary for Chlorodifluoromethane (PDF 12 pp, 119 K)  Not Available  Yes
Endocrine
Urinary
None
97 Chloroform 67-66-3 20011019Oct-19-2001 IRIS Summary for Chloroform (PDF 41 pp, 234 K) Toxicological Review for Chloroform (PDF 112 pp, 759 K)  No
Hepatic
Hepatic
98 Chloromethyl methyl ether (CMME) 107-30-2 19870930Sep-30-1987 IRIS Summary for Chloromethyl methyl ether (CMME) (PDF 9 pp, 97 K)  Not Available  No
None
None
99 beta-Chloronaphthalene 91-58-7 19901101Nov-01-1990 IRIS Summary for beta-Chloronaphthalene (PDF 6 pp, 93 K)  Not Available  No
Hepatic
Respiratory
None
100 2-Chlorophenol 95-57-8 19880822Aug-22-1988 IRIS Summary for 2-Chlorophenol (PDF 6 pp, 95 K)  Not Available  Yes
Reproductive
None
101 p-Chlorophenyl methyl sulfide 123-09-1 19930601Jun-01-1993 IRIS Summary for p-Chlorophenyl methyl sulfide (PDF 7 pp, 96 K)  Not Available  No
None
None
102 p-Chlorophenyl methyl sulfone 98-57-7 19930601Jun-01-1993 IRIS Summary for p-Chlorophenyl methyl sulfone (PDF 7 pp, 95 K)  Not Available  Yes
None
None
103 p-Chlorophenyl methyl sulfoxide 934-73-6 19930601Jun-01-1993 IRIS Summary for p-Chlorophenyl methyl sulfoxide (PDF 7 pp, 95 K)  Not Available  Yes
None
None
104 Chloroprene 126-99-8 20100930Sep-30-2010 IRIS Summary for Chloroprene (PDF 30 pp, 0.31 M) Toxicological Review for Chloroprene (PDF 303 pp, 4.63 M)
Chloroprene Support Documents
 No
Immune
Nervous
Respiratory
Dermal
Gastrointestinal
Hepatic
Ocular
Reproductive
Respiratory
105 o-Chlorotoluene 95-49-8 19900201Feb-01-1990 IRIS Summary for o-Chlorotoluene (PDF 7 pp, 89 K)  Not Available  Yes
None
None
106 Chromium(III), insoluble salts 16065-83-1 19980903Sep-03-1998 IRIS Summary for Chromium(III), insoluble salts (PDF 17 pp, 136 K) Toxicological Review for Chromium(III), insoluble salts (PDF 77 pp, 497 K)  Yes
None
None
107 Chromium(VI) 18540-29-9 19980903Sep-03-1998 IRIS Summary for Chromium(VI) (PDF 34 pp, 203 K) Toxicological Review for Chromium(VI) (PDF 70 pp, 195 K)  Yes
Respiratory
Respiratory
108 Chrysene 218-01-9 19901201Dec-01-1990 IRIS Summary for Chrysene (PDF 10 pp, 102 K)  Not Available  No
None
None
109 Coke oven emissions 19890501May-01-1989 IRIS Summary for Coke oven emissions (PDF 13 pp, 114 K)  Not Available  Yes
None
Respiratory
110 Copper cyanide 544-92-3 19880907Sep-07-1988 IRIS Summary for Copper cyanide (PDF 8 pp, 95 K)  Not Available  No
Hepatic
Urinary
None
111 Crotonaldehyde 123-73-9 19910601Jun-01-1991 IRIS Summary for Crotonaldehyde (PDF 8 pp, 101 K)  Not Available  No
None
None
112 Cumene 98-82-8 19970801Aug-01-1997 IRIS Summary for Cumene (PDF 22 pp, 155 K) Toxicological Review for Cumene (PDF 35 pp, 174 K)  Yes
Endocrine
Urinary
None
113 Cyanide, free 57-12-5 20100928Sep-28-2010 IRIS Summary for Cyanide, free (PDF 27 pp, 243 K) Toxicological Review for Cyanide, free (PDF 153 pp, 905 K)  Yes
Reproductive
None
114 Cyanogen 460-19-5 20100928Sep-28-2010 IRIS Summary for Cyanogen (PDF 27 pp, 243 K) Toxicological Review for Cyanogen (PDF 153 pp, 910 K)  Yes
None
None
115 Cyanogen bromide 506-68-3 19880926Sep-26-1988 IRIS Summary for Cyanogen bromide (PDF 8 pp, 93 K)  Not Available  No
Endocrine
Nervous
None
116 Cyclohexane 110-82-7 20030911Sep-11-2003 IRIS Summary for Cyclohexane (PDF 16 pp, 0.18 M) Toxicological Review for Cyclohexane (PDF 87 pp, 4.80 M)  No
Developmental
None
117 Cyclohexanone 108-94-1 19870930Sep-30-1987 IRIS Summary for Cyclohexanone (PDF 7 pp, 95 K)  Not Available  Yes
None
None
118 Cyclohexylamine 108-91-8 19880907Sep-07-1988 IRIS Summary for Cyclohexylamine (PDF 7 pp, 90 K)  Not Available  Yes
Reproductive
None
119 Dalapon, sodium salt 75-99-0 19880822Aug-22-1988 IRIS Summary for Dalapon, sodium salt (PDF 7 pp, 90 K)  Not Available  Yes
Urinary
None
120 2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether (BDE-209) 1163-19-5 20080630Jun-30-2008 IRIS Summary for 2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether (BDE-209) (PDF 25 pp, 232 K) Toxicological Review for 2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether (BDE-209) (PDF 126 pp, 820 K)  Yes
Nervous
Hepatic
121 Demeton 8065-48-3 19870131Jan-31-1987 IRIS Summary for Demeton (PDF 8 pp, 92 K)  Not Available  Yes
Nervous
None
122 Di (2-ethylhexyl)phthalate (DEHP) 117-81-7 19880907Sep-07-1988 IRIS Summary for Di (2-ethylhexyl)phthalate (DEHP) (PDF 14 pp, 121 K)  Not Available  No
Hepatic
Hepatic
123 Di(2-ethylhexyl)adipate 103-23-1 19920701Jul-01-1992 IRIS Summary for Di(2-ethylhexyl)adipate (PDF 17 pp, 135 K)  Not Available  No
Developmental
Hepatic
Musculoskeletal
Urinary
Hepatic
124 2,4-Diaminotoluene 95-80-7 19910301Mar-01-1991 IRIS Summary for 2,4-Diaminotoluene (PDF 6 pp, 92 K)  Not Available  Yes
None
None
125 Diazomethane 334-88-3 19911101Nov-01-1991 IRIS Summary for Diazomethane (PDF 4 pp, 81 K)  Not Available  Yes
None
None
126 Dibenz[a,h]anthracene 53-70-3 19901201Dec-01-1990 IRIS Summary for Dibenz[a,h]anthracene (PDF 12 pp, 114 K)  Not Available  No
None
None
127 Dibenzofuran 132-64-9 19901001Oct-01-1990 IRIS Summary for Dibenzofuran (PDF 6 pp, 86 K)  Not Available  Yes
None
None
128 1,2-Dibromo-3-chloropropane (DBCP) 96-12-8 19911001Oct-01-1991 IRIS Summary for 1,2-Dibromo-3-chloropropane (DBCP) (PDF 16 pp, 130 K)  Not Available  Yes
Reproductive
None
129 1,4-Dibromobenzene 106-37-6 19870331Mar-31-1987 IRIS Summary for 1,4-Dibromobenzene (PDF 6 pp, 85 K)  Not Available  No
Hepatic
None
130 Dibromochloromethane 124-48-1 19920101Jan-01-1992 IRIS Summary for Dibromochloromethane (PDF 13 pp, 116 K)  Not Available  Yes
Hepatic
Hepatic
131 Dibromodichloromethane 594-18-3 19910301Mar-01-1991 IRIS Summary for Dibromodichloromethane (PDF 5 pp, 87 K)  Not Available  No
None
None
132 p,p'-Dibromodiphenyl ether 2050-47-7 19900801Aug-01-1990 IRIS Summary for p,p'-Dibromodiphenyl ether (PDF 6 pp, 89 K)  Not Available  No
None
None
133 1,2-Dibromoethane 106-93-4 20040729Jul-29-2004 IRIS Summary for 1,2-Dibromoethane (PDF 34 pp, 0.24 M) Toxicological Review for 1,2-Dibromoethane (PDF 240 pp, 3.73 M)  No
Endocrine
Hepatic
Reproductive
Respiratory
Endocrine
Gastrointestinal
Reproductive
Respiratory
134 Dibutyl phthalate (DBP) 84-74-2 19901001Oct-01-1990 IRIS Summary for Dibutyl phthalate (DBP) (PDF 11 pp, 107 K)  Not Available  Yes
None
None
135 Dichloroacetic acid 79-43-6 20030911Sep-11-2003 IRIS Summary for Dichloroacetic acid (PDF 40 pp, 0.32 M) Toxicological Review for Dichloroacetic acid (PDF 192 pp, 1.71 M)  No
Hepatic
Nervous
Reproductive
Hepatic
136 1,2-Dichlorobenzene 95-50-1 19901101Nov-01-1990 IRIS Summary for 1,2-Dichlorobenzene (PDF 11 pp, 106 K)  Not Available  No
None
None
137 1,3-Dichlorobenzene 541-73-1 19900901Sep-01-1990 IRIS Summary for 1,3-Dichlorobenzene (PDF 6 pp, 82 K)  Not Available  No
None
None
138 1,4-Dichlorobenzene 106-46-7 19940101Jan-01-1994 IRIS Summary for 1,4-Dichlorobenzene (PDF 11 pp, 115 K)  Not Available  No
Hepatic
None
139 3,3'-Dichlorobenzidine 91-94-1 19911101Nov-01-1991 IRIS Summary for 3,3'-Dichlorobenzidine (PDF 11 pp, 112 K)  Not Available  No
None
Reproductive
140 Dichlorodifluoromethane 75-71-8 19870131Jan-31-1987 IRIS Summary for Dichlorodifluoromethane (PDF 7 pp, 90 K)  Not Available  No
None
None
141 p,p'-Dichlorodiphenyl dichloroethane (DDD) 72-54-8 19880822Aug-22-1988 IRIS Summary for p,p'-Dichlorodiphenyl dichloroethane (DDD) (PDF 9 pp, 97 K)  Not Available  Yes
None
Hepatic
142 p,p'-Dichlorodiphenyldichloroethylene (DDE) 72-55-9 19880822Aug-22-1988 IRIS Summary for p,p'-Dichlorodiphenyldichloroethylene (DDE) (PDF 10 pp, 102 K)  Not Available  Yes
None
Hepatic
143 p,p'-Dichlorodiphenyltrichloroethane (DDT) 50-29-3 19880822Aug-22-1988 IRIS Summary for p,p'-Dichlorodiphenyltrichloroethane (DDT) (PDF 17 pp, 133 K)  Not Available  Yes
Hepatic
Hepatic
144 1,1-Dichloroethane 75-34-3 19901001Oct-01-1990 IRIS Summary for 1,1-Dichloroethane (PDF 10 pp, 102 K)  Not Available  Yes
None
None
145 1,2-Dichloroethane 107-06-2 19870331Mar-31-1987 IRIS Summary for 1,2-Dichloroethane (PDF 11 pp, 108 K)  Not Available  No
None
None
146 cis-1,2-Dichloroethylene 156-59-2 20100930Sep-30-2010 IRIS Summary for cis-1,2-Dichloroethylene (PDF 16 pp, 0.18 M) Toxicological Review for cis-1,2-Dichloroethylene (PDF 174 pp, 1.18 M)  Yes
Urinary
None
147 trans-1,2-Dichloroethylene 156-60-5 20100930Sep-30-2010 IRIS Summary for trans-1,2-Dichloroethylene (PDF 22 pp, 0.22 M) Toxicological Review for trans-1,2-Dichloroethylene (PDF 174 pp, 1.18 M)  Yes
Immune
None
148 1,1-Dichloroethylene (1,1-DCE) 75-35-4 20020813Aug-13-2002 IRIS Summary for 1,1-Dichloroethylene (1,1-DCE) (PDF 37 pp, 225 K) Toxicological Review for 1,1-Dichloroethylene (1,1-DCE) (PDF 72 pp, 531 K)  No
Hepatic
None
149 Dichloromethane 75-09-2 20111118Nov-18-2011 IRIS Summary for Dichloromethane (PDF 44 pp, 0.34 M) Toxicological Review for Dichloromethane (PDF 567 pp, 5.10 M)  Yes
Hepatic
Hepatic
Respiratory
150 2,4-Dichlorophenol 120-83-2 19870131Jan-31-1987 IRIS Summary for 2,4-Dichlorophenol (PDF 7 pp, 88 K)  Not Available  Yes
Immune
None
151 1,2-Dichloropropane 78-87-5 19911201Dec-01-1991 IRIS Summary for 1,2-Dichloropropane (PDF 15 pp, 33 K)  Not Available  Yes
Respiratory
None
152 2,3-Dichloropropanol 616-23-9 19901101Nov-01-1990 IRIS Summary for 2,3-Dichloropropanol (PDF 6 pp, 85 K)  Not Available  No
Cardiovascular
Hepatic
Urinary
None
153 1,3-Dichloropropene 542-75-6 20000525May-25-2000 IRIS Summary for 1,3-Dichloropropene (PDF 34 pp, 213 K) Toxicological Review for 1,3-Dichloropropene (PDF 83 pp, 394 K)  Yes
Gastrointestinal
Respiratory
Hepatic
Respiratory
Urinary
154 Dieldrin 60-57-1 19880907Sep-07-1988 IRIS Summary for Dieldrin (PDF 18 pp, 135 K)  Not Available  Yes
Hepatic
Hepatic
155 Diesel engine exhaust 20030228Feb-28-2003 IRIS Summary for Diesel engine exhaust (PDF 36 pp, 297 K)  Not Available  No
Respiratory
None
156 Diethyl phthalate (DEP) 84-66-2 19880907Sep-07-1988 IRIS Summary for Diethyl phthalate (DEP) (PDF 10 pp, 103 K)  Not Available  Yes
None
None
157 Diethyl sulfate 64-67-5 19911101Nov-01-1991 IRIS Summary for Diethyl sulfate (PDF 4 pp, 84 K)  Not Available  Yes
None
None
158 Diethyl-p-nitrophenylphosphate 311-45-5 19921001Oct-01-1992 IRIS Summary for Diethyl-p-nitrophenylphosphate (PDF 7 pp, 94 K)  Not Available  No
None
None
159 Diethylene glycol dinitrate (DEGDN) 693-21-0 19930201Feb-01-1993 IRIS Summary for Diethylene glycol dinitrate (DEGDN) (PDF 6 pp, 91 K)  Not Available  No
None
None
160 1,1-Difluoroethane 75-37-6 19940901Sep-01-1994 IRIS Summary for 1,1-Difluoroethane (PDF 11 pp, 115 K)  Not Available  No
None
None
161 Diisopropyl methylphosphonate (DIMP) 1445-75-6 19890401Apr-01-1989 IRIS Summary for Diisopropyl methylphosphonate (DIMP) (PDF 12 pp, 111 K)  Not Available  Yes
None
None
162 Dimethyl phthalate 131-11-3 19900901Sep-01-1990 IRIS Summary for Dimethyl phthalate (PDF 8 pp, 93 K)  Not Available  Yes
None
None
163 Dimethyl sulfate 77-78-1 19920101Jan-01-1992 IRIS Summary for Dimethyl sulfate (PDF 10 pp, 100 K)  Not Available  Yes
None
None
164 Dimethyl terephthalate (DMT) 120-61-6 19870131Jan-31-1987 IRIS Summary for Dimethyl terephthalate (DMT) (PDF 7 pp, 89 K)  Not Available  Yes
Urinary
None
165 Dimethylamine 124-40-3 19910101Jan-01-1991 IRIS Summary for Dimethylamine (PDF 4 pp, 76 K)  Not Available  Yes
None
None
166 N-N-Dimethylaniline 121-69-7 19870930Sep-30-1987 IRIS Summary for N-N-Dimethylaniline (PDF 7 pp, 89 K)  Not Available  Yes
Hematologic
Immune
None
167 3,3-Dimethylbenzidine 119-93-7 19910701Jul-01-1991 IRIS Summary for 3,3-Dimethylbenzidine (PDF 5 pp, 88 K)  Not Available  Yes
None
None
168 N,N-Dimethylformamide 68-12-2 19901001Oct-01-1990 IRIS Summary for N,N-Dimethylformamide (PDF 16 pp, 126 K)  Not Available  Yes
Hepatic
None
169 2,4-Dimethylphenol 105-67-9 19901101Nov-01-1990 IRIS Summary for 2,4-Dimethylphenol (PDF 7 pp, 88 K)  Not Available  Yes
Hematologic
Nervous
None
170 2,6-Dimethylphenol 576-26-1 19880907Sep-07-1988 IRIS Summary for 2,6-Dimethylphenol (PDF 6 pp, 86 K)  Not Available  No
Hepatic
Immune
Urinary
None
171 3,4-Dimethylphenol 95-65-8 19880907Sep-07-1988 IRIS Summary for 3,4-Dimethylphenol (PDF 7 pp, 87 K)  Not Available  No
Cardiovascular
Hepatic
Immune
Urinary
None
172 4,6-Dinitro-o-cyclohexyl phenol 131-89-5 19880822Aug-22-1988 IRIS Summary for 4,6-Dinitro-o-cyclohexyl phenol (PDF 7 pp, 90 K)  Not Available  Yes
Ocular
None
173 m-Dinitrobenzene 99-65-0 19910301Mar-01-1991 IRIS Summary for m-Dinitrobenzene (PDF 10 pp, 101 K)  Not Available  No
Immune
None
174 o-Dinitrobenzene 528-29-0 19920901Sep-01-1992 IRIS Summary for o-Dinitrobenzene (PDF 7 pp, 94 K)  Not Available  No
None
None
175 2,4-Dinitrophenol 51-28-5 19911001Oct-01-1991 IRIS Summary for 2,4-Dinitrophenol (PDF 8 pp, 95 K)  Not Available  No
Ocular
None
176 2,4-Dinitrotoluene 121-14-2 19920601Jun-01-1992 IRIS Summary for 2,4-Dinitrotoluene (PDF 13 pp, 126 K)  Not Available  Yes
Hematologic
Hepatic
Nervous
None
177 2,4-/2,6-Dinitrotoluene mixture 19900901Sep-01-1990 IRIS Summary for 2,4-/2,6-Dinitrotoluene mixture (PDF 12 pp, 110 K)  Not Available  Yes
None
Hepatic
Reproductive
178 Dinoseb 88-85-7 19890801Aug-01-1989 IRIS Summary for Dinoseb (PDF 12 pp, 111 K)  Not Available  Yes
Developmental
None
179 1,4-Dioxane 123-91-1 20130920Sep-20-2013 IRIS Summary for 1,4-Dioxane (PDF 25 pp, 0.27 M) Toxicological Review for 1,4-Dioxane (PDF 419 pp, 8.52 M)  Yes
Hepatic
Nervous
Respiratory
Urinary
Gastrointestinal
Hepatic
Reproductive
Respiratory
Urinary
180 Diphenamid 957-51-7 19870930Sep-30-1987 IRIS Summary for Diphenamid (PDF 6 pp, 87 K)  Not Available  Yes
Hepatic
None
181 1,2-Diphenylhydrazine 122-66-7 19911101Nov-01-1991 IRIS Summary for 1,2-Diphenylhydrazine (PDF 11 pp, 107 K)  Not Available  No
None
Hepatic
182 1,4-Dithiane 505-29-3 19930301Mar-01-1993 IRIS Summary for 1,4-Dithiane (PDF 10 pp, 108 K)  Not Available  No
Nervous
Respiratory
None
183 Endrin 72-20-8 19891001Oct-01-1989 IRIS Summary for Endrin (PDF 11 pp, 108 K)  Not Available  Yes
Hepatic
Nervous
None
184 Epichlorohydrin 106-89-8 19920401Apr-01-1992 IRIS Summary for Epichlorohydrin (PDF 24 pp, 167 K)  Not Available  Yes
Respiratory
Gastrointestinal
Respiratory
185 1,2-Epoxybutane (EBU) 106-88-7 19920501May-01-1992 IRIS Summary for 1,2-Epoxybutane (EBU) (PDF 13 pp, 121 K)  Not Available  Yes
Respiratory
None
186 2-Ethoxyethanol 110-80-5 19910501May-01-1991 IRIS Summary for 2-Ethoxyethanol (PDF 11 pp, 113 K)  Not Available  Yes
Hematologic
Reproductive
None
187 Ethyl acetate 141-78-6 19870301Mar-01-1987 IRIS Summary for Ethyl acetate (PDF 6 pp, 87 K)  Not Available  Yes
None
None
188 Ethyl carbamate 51-79-6 19920401Apr-01-1992 IRIS Summary for Ethyl carbamate (PDF 4 pp, 83 K)  Not Available  Yes
None
None
189 Ethyl chloride 75-00-3 19910401Apr-01-1991 IRIS Summary for Ethyl chloride (PDF 12 pp, 121 K)  Not Available  No
Developmental
Musculoskeletal
None
190 Ethyl ether 60-29-7 19900901Sep-01-1990 IRIS Summary for Ethyl ether (PDF 7 pp, 89 K)  Not Available  Yes
None
None
191 Ethyl p-nitrophenyl phenylphosphorothioate (EPN) 2104-64-5 19870930Sep-30-1987 IRIS Summary for Ethyl p-nitrophenyl phenylphosphorothioate (EPN) (PDF 7 pp, 90 K)  Not Available  Yes
Nervous
None
192 Ethylbenzene 100-41-4 19910301Mar-01-1991 IRIS Summary for Ethylbenzene (PDF 21 pp, 148 K)  Not Available  No
Developmental
Hepatic
Urinary
None
193 Ethylene diamine 107-15-3 19921101Nov-01-1992 IRIS Summary for Ethylene diamine (PDF 9 pp, 105 K)  Not Available  Yes
None
None
194 Ethylene glycol 107-21-1 19870930Sep-30-1987 IRIS Summary for Ethylene glycol (PDF 8 pp, 92 K)  Not Available  Yes
Urinary
None
195 Ethylene glycol monobutyl ether (EGBE) (2-Butoxyethanol) 111-76-2 20100331Mar-31-2010 IRIS Summary for Ethylene glycol monobutyl ether (EGBE) (2-Butoxyethanol) (PDF 31 pp, 0.30 M) Toxicological Review for Ethylene glycol monobutyl ether (EGBE) (2-Butoxyethanol) (PDF 206 pp, 3.65 M)  No
Hematologic
None
196 Ethylene oxide 75-21-8 20161216Dec-16-2016 IRIS Summary for Ethylene oxide (PDF 9 pp, 0.21 M) Toxicological Review for Ethylene oxide (PDF 228 pp, 1.85 M)
Ethylene oxide Support Documents
 No
None
Immune
Reproductive
197 Ethylene thiourea (ETU) 96-45-7 19910501May-01-1991 IRIS Summary for Ethylene thiourea (ETU) (PDF 10 pp, 105 K)  Not Available  Yes
Endocrine
None
198 Ethyleneimine 151-56-4 19920401Apr-01-1992 IRIS Summary for Ethyleneimine (PDF 4 pp, 84 K)  Not Available  Yes
None
None
199 Ethylphthalyl ethylglycolate (EPEG) 84-72-0 19870131Jan-31-1987 IRIS Summary for Ethylphthalyl ethylglycolate (EPEG) (PDF 6 pp, 86 K)  Not Available  No
Urinary
None
200 Fluoranthene 206-44-0 19901201Dec-01-1990 IRIS Summary for Fluoranthene (PDF 12 pp, 109 K)  Not Available  No
Hepatic
Urinary
None
201 Fluorene 86-73-7 19901201Dec-01-1990 IRIS Summary for Fluorene (PDF 11 pp, 106 K)  Not Available  No
Hematologic
None
202 Fluorine (soluble fluoride) 7782-41-4 19870131Jan-31-1987 IRIS Summary for Fluorine (soluble fluoride) (PDF 7 pp, 90 K)  Not Available  Yes
Gastrointestinal
None
203 Formaldehyde 50-00-0 19900901Sep-01-1990 IRIS Summary for Formaldehyde (PDF 17 pp, 133 K)  Not Available Formaldehyde Support Documents  No
Gastrointestinal
Urinary
Respiratory
204 Furan 110-00-9 19870131Jan-31-1987 IRIS Summary for Furan (PDF 7 pp, 89 K)  Not Available  Yes
Hepatic
None
205 Furmecyclox 60568-05-0 19880907Sep-07-1988 IRIS Summary for Furmecyclox (PDF 8 pp, 94 K)  Not Available  Yes
None
Hepatic
206 Glycidaldehyde 765-34-4 19910801Aug-01-1991 IRIS Summary for Glycidaldehyde (PDF 15 pp, 121 K)  Not Available  No
Endocrine
Hematologic
Urinary
None
207 Heptachlor 76-44-8 19870930Sep-30-1987 IRIS Summary for Heptachlor (PDF 14 pp, 122 K)  Not Available  Yes
Hepatic
Hepatic
208 n-Heptane 142-82-5 19930101Jan-01-1993 IRIS Summary for n-Heptane (PDF 6 pp, 89 K)  Not Available  Yes
None
None
209 Hexabromobenzene 87-82-1 19870331Mar-31-1987 IRIS Summary for Hexabromobenzene (PDF 7 pp, 90 K)  Not Available  No
Hepatic
None
210 Hexabromodiphenyl ether 36483-60-0 19900801Aug-01-1990 IRIS Summary for Hexabromodiphenyl ether (PDF 6 pp, 82 K)  Not Available  Yes
None
None
211 2,2',4,4',5,5'-Hexabromodiphenyl ether (BDE-153) 68631-49-2 20080630Jun-30-2008 IRIS Summary for 2,2',4,4',5,5'-Hexabromodiphenyl ether (BDE-153) (PDF 15 pp, 166 K) Toxicological Review for 2,2',4,4',5,5'-Hexabromodiphenyl ether (BDE-153) (PDF 66 pp, 301 K)  No
Nervous
None
212 Hexachlorobenzene 118-74-1 19910301Mar-01-1991 IRIS Summary for Hexachlorobenzene (PDF 16 pp, 129 K)  Not Available  Yes
Hepatic
Hepatic
213 Hexachlorobutadiene 87-68-3 19930501May-01-1993 IRIS Summary for Hexachlorobutadiene (PDF 9 pp, 100 K)  Not Available  No
None
Urinary
214 alpha-Hexachlorocyclohexane (alpha-HCH) 319-84-6 19870331Mar-31-1987 IRIS Summary for alpha-Hexachlorocyclohexane (alpha-HCH) (PDF 10 pp, 104 K)  Not Available  Yes
None
Hepatic
215 beta-Hexachlorocyclohexane (beta-HCH) 319-85-7 19870930Sep-30-1987 IRIS Summary for beta-Hexachlorocyclohexane (beta-HCH) (PDF 9 pp, 98 K)  Not Available  Yes
None
Hepatic
216 delta-Hexachlorocyclohexane (delta-HCH) 319-86-8 19870331Mar-31-1987 IRIS Summary for delta-Hexachlorocyclohexane (delta-HCH) (PDF 6 pp, 85 K)  Not Available  Yes
None
None
217 epsilon-Hexachlorocyclohexane (epsilon-HC) 6108-10-7 19870331Mar-31-1987 IRIS Summary for epsilon-Hexachlorocyclohexane (epsilon-HC) (PDF 5 pp, 81 K)  Not Available  Yes
None
None
218 Hexachlorocyclopentadiene (HCCPD) 77-47-4 20010705Jul-05-2001 IRIS Summary for Hexachlorocyclopentadiene (HCCPD) (PDF 25 pp, 172 K) Toxicological Review for Hexachlorocyclopentadiene (HCCPD) (PDF 60 pp, 237 K)  Yes
Gastrointestinal
Respiratory
None
219 Hexachlorodibenzo-p-dioxin (HxCDD), mixture of 1,2,3,6,7,8-HxCDD and 1,2,3,7,8,9-HxCDD 57653-85-7 19870331Mar-31-1987 IRIS Summary for Hexachlorodibenzo-p-dioxin (HxCDD), mixture of 1,2,3,6,7,8-HxCDD and 1,2,3,7,8,9-HxCDD (PDF 10 pp, 102 K)  Not Available  Yes
None
Hepatic
220 Hexachloroethane 67-72-1 20110923Sep-23-2011 IRIS Summary for Hexachloroethane (PDF 34 pp, 0.31 M) Toxicological Review for Hexachloroethane (PDF 200 pp, 1.61 M)  Yes
Nervous
Urinary
Urinary
221 Hexachlorophene 70-30-4 19880822Aug-22-1988 IRIS Summary for Hexachlorophene (PDF 8 pp, 93 K)  Not Available  Yes
Gastrointestinal
Nervous
None
222 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) 121-82-4 20180830Aug-30-2018 IRIS Summary for Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) (PDF 7 pp, 0.90 M) Toxicological Review for Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) (PDF 187 pp, 2.60 M)
Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) Support Documents
 No
Nervous
Reproductive
Urinary
Hepatic
Respiratory
223 1,6-Hexamethylene diisocyanate 822-06-0 19940901Sep-01-1994 IRIS Summary for 1,6-Hexamethylene diisocyanate (PDF 14 pp, 126 K)  Not Available  Yes
Nervous
Respiratory
None
224 n-Hexane 110-54-3 20051223Dec-23-2005 IRIS Summary for n-Hexane (PDF 28 pp, 0.19 M) Toxicological Review for n-Hexane (PDF 210 pp, 1.40 M)  Yes
Nervous
None
225 2-Hexanone 591-78-6 20090925Sep-25-2009 IRIS Summary for 2-Hexanone (PDF 19 pp, 148 K) Toxicological Review for 2-Hexanone (PDF 136 pp, 964 K)  No
Nervous
None
226 Hydrazine/Hydrazine sulfate 302-01-2 19880907Sep-07-1988 IRIS Summary for Hydrazine/Hydrazine sulfate (PDF 14 pp, 119 K)  Not Available  Yes
None
Hepatic
Respiratory
227 Hydrogen Cyanide and Cyanide Salts Various 20100928Sep-28-2010 IRIS Summary for Hydrogen Cyanide and Cyanide Salts (PDF 27 pp, 243 K) Toxicological Review for Hydrogen Cyanide and Cyanide Salts (PDF 153 pp, 905 K)  No
Endocrine
Reproductive
None
228 Hydrogen chloride 7647-01-0 19950701Jul-01-1995 IRIS Summary for Hydrogen chloride (PDF 10 pp, 102 K)  Not Available  Yes
Respiratory
None
229 Hydrogen sulfide 7783-06-4 20030728Jul-28-2003 IRIS Summary for Hydrogen sulfide (PDF 18 pp, 0.14 M) Toxicological Review for Hydrogen sulfide (PDF 74 pp, 1.44 M)  No
Nervous
Respiratory
None
230 Hydroquinone 123-31-9 19901001Oct-01-1990 IRIS Summary for Hydroquinone (PDF 5 pp, 86 K)  Not Available  Yes
None
None
231 Indeno[1,2,3-cd]pyrene 193-39-5 19901201Dec-01-1990 IRIS Summary for Indeno[1,2,3-cd]pyrene (PDF 9 pp, 102 K)  Not Available  No
None
None
232 Isobutyl alcohol 78-83-1 19870331Mar-31-1987 IRIS Summary for Isobutyl alcohol (PDF 7 pp, 90 K)  Not Available  Yes
Nervous
None
233 Isophorone 78-59-1 19921001Oct-01-1992 IRIS Summary for Isophorone (PDF 15 pp, 125 K)  Not Available  Yes
Urinary
Reproductive
234 Isopropalin 33820-53-0 19870131Jan-31-1987 IRIS Summary for Isopropalin (PDF 7 pp, 88 K)  Not Available  Yes
Hematologic
None
235 Isopropyl methyl phosphonic acid (IMPA) 1832-54-8 19920601Jun-01-1992 IRIS Summary for Isopropyl methyl phosphonic acid (IMPA) (PDF 12 pp, 118 K)  Not Available  No
None
None
236 Lead and compounds (inorganic) 7439-92-1 20040708Jul-08-2004 IRIS Summary for Lead and compounds (inorganic) (PDF 15 pp, 128 K)  Not Available  Yes
None
None
237 Libby Amphibole asbestos 20141208Dec-08-2014 IRIS Summary for Libby Amphibole asbestos (PDF 36 pp, 0.36 M) Toxicological Review for Libby Amphibole asbestos (PDF 685 pp, 8.45 M)
Libby Amphibole asbestos Support Documents
 No
Respiratory
Respiratory
238 Maleic anhydride 108-31-6 19880822Aug-22-1988 IRIS Summary for Maleic anhydride (PDF 8 pp, 91 K)  Not Available  Yes
Urinary
None
239 Manganese 7439-96-5 19951101Nov-01-1995 IRIS Summary for Manganese (PDF 48 pp, 265 K)  Not Available  Yes
Nervous
None
240 Mercuric chloride (HgCl2) 7487-94-7 19950501May-01-1995 IRIS Summary for Mercuric chloride (HgCl2) (PDF 21 pp, 156 K)  Not Available  Yes
Immune
Urinary
None
241 Mercury, elemental 7439-97-6 19950601Jun-01-1995 IRIS Summary for Mercury, elemental (PDF 28 pp, 177 K)  Not Available  Yes
Nervous
None
242 Merphos 150-50-5 19921101Nov-01-1992 IRIS Summary for Merphos (PDF 8 pp, 92 K)  Not Available  Yes
Nervous
None
243 Methacrylonitrile 126-98-7 19880907Sep-07-1988 IRIS Summary for Methacrylonitrile (PDF 7 pp, 88 K)  Not Available  Yes
Hepatic
None
244 Methanol 67-56-1 20130930Sep-30-2013 IRIS Summary for Methanol (PDF 6 pp, 0.09 M) Toxicological Review for Methanol (PDF 212 pp, 3.46 M)  No
Developmental
Nervous
None
245 Methoxychlor 72-43-5 19931201Dec-01-1993 IRIS Summary for Methoxychlor (PDF 26 pp, 168 K)  Not Available  Yes
Developmental
None
246 2-Methoxyethanol 109-86-4 19910501May-01-1991 IRIS Summary for 2-Methoxyethanol (PDF 13 pp, 124 K)  Not Available  Yes
Reproductive
None
247 Methyl acrylate 96-33-3 19901201Dec-01-1990 IRIS Summary for Methyl acrylate (PDF 7 pp, 88 K)  Not Available  Yes
None
None
248 Methyl chloride 74-87-3 20010717Jul-17-2001 IRIS Summary for Methyl chloride (PDF 23 pp, 165 K) Toxicological Review for Methyl chloride (PDF 95 pp, 337 K)  Yes
Nervous
None
249 Methyl chlorocarbonate 79-22-1 19890501May-01-1989 IRIS Summary for Methyl chlorocarbonate (PDF 4 pp, 77 K)  Not Available  No
None
None
250 Methyl ethyl ketone (MEK) 78-93-3 20030926Sep-26-2003 IRIS Summary for Methyl ethyl ketone (MEK) (PDF 33 pp, 211 K) Toxicological Review for Methyl ethyl ketone (MEK) (PDF 152 pp, 570 K)  No
Developmental
Musculoskeletal
None
251 Methyl isobutyl ketone (MIBK) 108-10-1 20030425Apr-25-2003 IRIS Summary for Methyl isobutyl ketone (MIBK) (PDF 23 pp, 162 K) Toxicological Review for Methyl isobutyl ketone (MIBK) (PDF 68 pp, 547 K)  No
Developmental
Musculoskeletal
None
252 Methyl isocyanate 624-83-9 19910301Mar-01-1991 IRIS Summary for Methyl isocyanate (PDF 4 pp, 85 K)  Not Available  Yes
None
None
253 Methyl methacrylate 80-62-6 19980302Mar-02-1998 IRIS Summary for Methyl methacrylate (PDF 31 pp, 204 K) Toxicological Review for Methyl methacrylate (PDF 83 pp, 275 K)  No
Nervous
Respiratory
None
254 Methyl tert-butyl ether (MTBE) 1634-04-4 19930901Sep-01-1993 IRIS Summary for Methyl tert-butyl ether (MTBE) (PDF 25 pp, 170 K)  Not Available  No
Hepatic
Ocular
Urinary
None
255 Methylene Diphenyl Diisocyanate (monomeric MDI) and polymeric MDI (PMDI) 101-68-8 19980207Feb-07-1998 IRIS Summary for Methylene Diphenyl Diisocyanate (monomeric MDI) and polymeric MDI (PMDI) (PDF 23 pp, 170 K) Toxicological Review for Methylene Diphenyl Diisocyanate (monomeric MDI) and polymeric MDI (PMDI) (PDF 54 pp, 154 K)  Yes
Nervous
Respiratory
None
256 4,4'-Methylene bis(N,N'-dimethyl)aniline 101-61-1 19890801Aug-01-1989 IRIS Summary for 4,4'-Methylene bis(N,N'-dimethyl)aniline (PDF 10 pp, 104 K)  Not Available  No
None
Endocrine
257 Methylmercury (MeHg) 22967-92-6 20010727Jul-27-2001 IRIS Summary for Methylmercury (MeHg) (PDF 44 pp, 258 K)  Not Available Methylmercury (MeHg) Support Documents  Yes
Developmental
Nervous
None
258 2-Methylnaphthalene 91-57-6 20031222Dec-22-2003 IRIS Summary for 2-Methylnaphthalene (PDF 21 pp, 158 K) Toxicological Review for 2-Methylnaphthalene (PDF 97 pp, 242 K)  No
Respiratory
None
259 2-Methylphenol 95-48-7 19920401Apr-01-1992 IRIS Summary for 2-Methylphenol (PDF 16 pp, 126 K)  Not Available  Yes
Nervous
None
260 3-Methylphenol 108-39-4 19920401Apr-01-1992 IRIS Summary for 3-Methylphenol (PDF 16 pp, 125 K)  Not Available  Yes
Nervous
None
261 4-Methylphenol 106-44-5 19920401Apr-01-1992 IRIS Summary for 4-Methylphenol (PDF 13 pp, 114 K)  Not Available  Yes
None
None
262 Mirex 2385-85-5 19921001Oct-01-1992 IRIS Summary for Mirex (PDF 17 pp, 133 K)  Not Available  No
Endocrine
Hepatic
None
263 Molybdenum 7439-98-7 19921101Nov-01-1992 IRIS Summary for Molybdenum (PDF 11 pp, 106 K)  Not Available  Yes
Urinary
None
264 Monochloramine 10599-90-3 19940301Mar-01-1994 IRIS Summary for Monochloramine (PDF 19 pp, 149 K)  Not Available  No
None
None
265 Naphthalene 91-20-3 19980917Sep-17-1998 IRIS Summary for Naphthalene (PDF 32 pp, 102 K) Toxicological Review for Naphthalene (PDF 116 pp, 565 K)  No
Nervous
Respiratory
None
266 Nickel carbonyl 13463-39-3 19870930Sep-30-1987 IRIS Summary for Nickel carbonyl (PDF 7 pp, 88 K)  Not Available  Yes
None
None
267 Nickel refinery dust 19870930Sep-30-1987 IRIS Summary for Nickel refinery dust (PDF 10 pp, 104 K)  Not Available  No
None
Respiratory
268 Nickel subsulfide 12035-72-2 19870930Sep-30-1987 IRIS Summary for Nickel subsulfide (PDF 11 pp, 109 K)  Not Available  Yes
None
Respiratory
269 Nickel, soluble salts 19940801Aug-01-1994 IRIS Summary for Nickel, soluble salts (PDF 13 pp, 118 K)  Not Available  No
None
None
270 Nitrate 14797-55-8 19910501May-01-1991 IRIS Summary for Nitrate (PDF 12 pp, 106 K)  Not Available  Yes
Hematologic
None
271 Nitric oxide 10102-43-9 19940901Sep-01-1994 IRIS Summary for Nitric oxide (PDF 5 pp, 80 K)  Not Available  Yes
None
None
272 Nitrite 14797-65-0 19870131Jan-31-1987 IRIS Summary for Nitrite (PDF 7 pp, 90 K)  Not Available  Yes
Hematologic
None
273 Nitrobenzene 98-95-3 20090206Feb-06-2009 IRIS Summary for Nitrobenzene (PDF 30 pp, 0.26 M) Toxicological Review for Nitrobenzene (PDF 250 pp, 3.83 M)  No
Hematologic
Nervous
Respiratory
Endocrine
Hepatic
Urinary
274 Nitrogen dioxide 10102-44-0 19940901Sep-01-1994 IRIS Summary for Nitrogen dioxide (PDF 5 pp, 82 K)  Not Available  Yes
None
None
275 Nitroguanidine 556-88-7 19900901Sep-01-1990 IRIS Summary for Nitroguanidine (PDF 11 pp, 107 K)  Not Available  Yes
Developmental
None
276 2-Nitropropane 79-46-9 19910301Mar-01-1991 IRIS Summary for 2-Nitropropane (PDF 10 pp, 110 K)  Not Available  Yes
Hepatic
None
277 N-Nitroso-N-methylethylamine 10595-95-6 19880301Mar-01-1988 IRIS Summary for N-Nitroso-N-methylethylamine (PDF 9 pp, 96 K)  Not Available  Yes
None
Hepatic
278 N-Nitroso-di-n-butylamine 924-16-3 19870131Jan-31-1987 IRIS Summary for N-Nitroso-di-n-butylamine (PDF 10 pp, 101 K)  Not Available  Yes
None
Gastrointestinal
Urinary
279 N-Nitrosodi-N-propylamine 621-64-7 19870331Mar-31-1987 IRIS Summary for N-Nitrosodi-N-propylamine (PDF 11 pp, 104 K)  Not Available  Yes
None
Hepatic
280 N-Nitrosodiethanolamine 1116-54-7 19870930Sep-30-1987 IRIS Summary for N-Nitrosodiethanolamine (PDF 9 pp, 98 K)  Not Available  Yes
None
Hepatic
281 N-Nitrosodiethylamine 55-18-5 19870131Jan-31-1987 IRIS Summary for N-Nitrosodiethylamine (PDF 11 pp, 106 K)  Not Available  Yes
None
Hepatic
282 N-Nitrosodimethylamine 62-75-9 19870131Jan-31-1987 IRIS Summary for N-Nitrosodimethylamine (PDF 11 pp, 105 K)  Not Available  Yes
None
Hepatic
283 N-Nitrosodiphenylamine 86-30-6 19870331Mar-31-1987 IRIS Summary for N-Nitrosodiphenylamine (PDF 10 pp, 102 K)  Not Available  Yes
None
Urinary
284 N-Nitrosopyrrolidine 930-55-2 19870131Jan-31-1987 IRIS Summary for N-Nitrosopyrrolidine (PDF 10 pp, 102 K)  Not Available  Yes
None
Hepatic
285 Nonabromodiphenyl ether 63936-56-1 19900801Aug-01-1990 IRIS Summary for Nonabromodiphenyl ether (PDF 5 pp, 87 K)  Not Available  Yes
None
None
286 Octabromodiphenyl ether 32536-52-0 19900801Aug-01-1990 IRIS Summary for Octabromodiphenyl ether (PDF 8 pp, 93 K)  Not Available  Yes
Hepatic
None
287 Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) 2691-41-0 19890301Mar-01-1989 IRIS Summary for Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) (PDF 11 pp, 107 K)  Not Available  Yes
Hepatic
None
288 Pentabromodiphenyl ether 32534-81-9 19900801Aug-01-1990 IRIS Summary for Pentabromodiphenyl ether (PDF 9 pp, 96 K)  Not Available  Yes
Hepatic
None
289 2,2',4,4',5-Pentabromodiphenyl ether (BDE-99) 60348-60-9 20080630Jun-30-2008 IRIS Summary for 2,2',4,4',5-Pentabromodiphenyl ether (BDE-99) (PDF 20 pp, 0.16 M) Toxicological Review for 2,2',4,4',5-Pentabromodiphenyl ether (BDE-99) (PDF 128 pp, 1.37 M)  No
Nervous
None
290 Pentachlorobenzene 608-93-5 19921101Nov-01-1992 IRIS Summary for Pentachlorobenzene (PDF 10 pp, 101 K)  Not Available  Yes
Hepatic
Urinary
None
291 Pentachlorocyclopentadiene 25329-35-5 19900301Mar-01-1990 IRIS Summary for Pentachlorocyclopentadiene (PDF 5 pp, 81 K)  Not Available  No
None
None
292 Pentachlorophenol 87-86-5 20100930Sep-30-2010 IRIS Summary for Pentachlorophenol (PDF 27 pp, 0.26 M) Toxicological Review for Pentachlorophenol (PDF 288 pp, 2.23 M)  No
Hepatic
Endocrine
Hepatic
293 Pentafluoroethane 354-33-6 19931201Dec-01-1993 IRIS Summary for Pentafluoroethane (PDF 7 pp, 94 K)  Not Available  Yes
None
None
294 Perchlorate (ClO4) and Perchlorate Salts 7790-98-9 20050218Feb-18-2005 IRIS Summary for Perchlorate (ClO4) and Perchlorate Salts (PDF 22 pp, 157 K)  Not Available Perchlorate (ClO4) and Perchlorate Salts Support Documents  No
Endocrine
None
295 Phenanthrene 85-01-8 19901201Dec-01-1990 IRIS Summary for Phenanthrene (PDF 11 pp, 103 K)  Not Available  No
None
None
296 Phenol 108-95-2 20020930Sep-30-2002 IRIS Summary for Phenol (PDF 31 pp, 0.19 M) Toxicological Review for Phenol (PDF 213 pp, 2.96 M)  Yes
None
None
297 m-Phenylenediamine 108-45-2 19870131Jan-31-1987 IRIS Summary for m-Phenylenediamine (PDF 7 pp, 87 K)  Not Available  Yes
Hepatic
None
298 Phenylmercuric acetate 62-38-4 19870131Jan-31-1987 IRIS Summary for Phenylmercuric acetate (PDF 7 pp, 90 K)  Not Available  Yes
Urinary
None
299 Phosgene 75-44-5 20060131Jan-31-2006 IRIS Summary for Phosgene (PDF 22 pp, 166 K) Toxicological Review for Phosgene (PDF 102 pp, 614 K)  No
Respiratory
None
300 Phosphine 7803-51-2 19950701Jul-01-1995 IRIS Summary for Phosphine (PDF 146 pp, 20 K)  Not Available  Yes
None
None
301 Phosphoric acid 7664-38-2 19950801Aug-01-1995 IRIS Summary for Phosphoric acid (PDF 17 pp, 137 K)  Not Available  No
Respiratory
None
302 Phthalic anhydride 85-44-9 19880907Sep-07-1988 IRIS Summary for Phthalic anhydride (PDF 7 pp, 88 K)  Not Available  Yes
Respiratory
Urinary
None
303 Polychlorinated biphenyls (PCBs) 1336-36-3 19961001Oct-01-1996 IRIS Summary for Polychlorinated biphenyls (PCBs) (PDF 22 pp, 150 K)  Not Available  No
None
Hepatic
304 Potassium cyanide 151-50-8 20100928Sep-28-2010 IRIS Summary for Potassium cyanide (PDF 27 pp, 243 K) Toxicological Review for Potassium cyanide (PDF 153 pp, 910 K)  Yes
Reproductive
None
305 Potassium silver cyanide 506-61-6 20100928Sep-28-2010 IRIS Summary for Potassium silver cyanide (PDF 27 pp, 243 K) Toxicological Review for Potassium silver cyanide (PDF 153 pp, 910 K)  Yes
Reproductive
None
306 Prochloraz 67747-09-5 19891001Oct-01-1989 IRIS Summary for Prochloraz (PDF 13 pp, 114 K)  Not Available  Yes
Hepatic
Hepatic
307 Propargyl alcohol 107-19-7 19901101Nov-01-1990 IRIS Summary for Propargyl alcohol (PDF 6 pp, 94 K)  Not Available  Yes
Hepatic
Urinary
None
308 Propham 122-42-9 19870930Sep-30-1987 IRIS Summary for Propham (PDF 6 pp, 86 K)  Not Available  Yes
Immune
Nervous
None
309 beta-Propiolactone 57-57-8 19910701Jul-01-1991 IRIS Summary for beta-Propiolactone (PDF 5 pp, 88 K)  Not Available  Yes
None
None
310 Propionaldehyde 123-38-6 20080930Sep-30-2008 IRIS Summary for Propionaldehyde (PDF 18 pp, 198 K) Toxicological Review for Propionaldehyde (PDF 78 pp, 559 K)  No
Nervous
Respiratory
None
311 Propylene glycol monoethyl ether 52125-53-8 19910601Jun-01-1991 IRIS Summary for Propylene glycol monoethyl ether (PDF 4 pp, 84 K)  Not Available  No
None
None
312 Propylene glycol monomethyl ether (PGME) 107-98-2 19910701Jul-01-1991 IRIS Summary for Propylene glycol monomethyl ether (PGME) (PDF 11 pp, 106 K)  Not Available  Yes
Nervous
None
313 Propylene oxide 75-56-9 19901101Nov-01-1990 IRIS Summary for Propylene oxide (PDF 22 pp, 157 K)  Not Available  Yes
Respiratory
Gastrointestinal
Respiratory
314 Propyleneimine 75-55-8 19920101Jan-01-1992 IRIS Summary for Propyleneimine (PDF 4 pp, 82 K)  Not Available  Yes
None
None
315 Pyrene 129-00-0 19900901Sep-01-1990 IRIS Summary for Pyrene (PDF 13 pp, 119 K)  Not Available  No
Urinary
None
316 Pyridine 110-86-1 19870930Sep-30-1987 IRIS Summary for Pyridine (PDF 7 pp, 94 K)  Not Available  Yes
Hepatic
None
317 Quinalphos 13593-03-8 19870331Mar-31-1987 IRIS Summary for Quinalphos (PDF 7 pp, 87 K)  Not Available  Yes
None
None
318 Quinoline 91-22-5 20010927Sep-27-2001 IRIS Summary for Quinoline (PDF 23 pp, 158 K) Toxicological Review for Quinoline (PDF 40 pp, 163 K)  No
None
Hepatic
319 Quinone 106-51-4 19901001Oct-01-1990 IRIS Summary for Quinone (PDF 5 pp, 86 K)  Not Available  Yes
None
None
320 Radium 226,228 Various 19890101Jan-01-1989 IRIS Summary for Radium 226,228 (PDF 4 pp, 76 K)  Not Available  Yes
None
None
321 Radon 222 14859-67-7 19890701Jul-01-1989 IRIS Summary for Radon 222 (PDF 4 pp, 78 K)  Not Available  Yes
None
None
322 Refractory ceramic fibers 19920901Sep-01-1992 IRIS Summary for Refractory ceramic fibers (PDF 10 pp, 180 K)  Not Available  No
None
None
323 Selenious acid 7783-00-8 19910601Jun-01-1991 IRIS Summary for Selenious acid (PDF 24 pp, 159 K)  Not Available  No
Dermal
Hematologic
Nervous
None
324 Selenium and Compounds 7782-49-2 19910601Jun-01-1991 IRIS Summary for Selenium and Compounds (PDF 24 pp, 166 K)  Not Available  Yes
Dermal
Hematologic
Nervous
None
325 Selenium sulfide 7446-34-6 19910301Mar-01-1991 IRIS Summary for Selenium sulfide (PDF 12 pp, 109 K)  Not Available  Yes
None
None
326 Selenourea 630-10-4 19910501May-01-1991 IRIS Summary for Selenourea (PDF 4 pp, 76 K)  Not Available  No
None
None
327 Silver 7440-22-4 19911201Dec-01-1991 IRIS Summary for Silver (PDF 14 pp, 120 K)  Not Available  Yes
Dermal
None
328 Silver cyanide 506-64-9 19870131Jan-31-1987 IRIS Summary for Silver cyanide (PDF 8 pp, 94 K)  Not Available  No
Endocrine
Nervous
None
329 Sodium azide 26628-22-8 19870331Mar-31-1987 IRIS Summary for Sodium azide (PDF 7 pp, 88 K)  Not Available  Yes
None
None
330 Sodium cyanide 143-33-9 20100928Sep-28-2010 IRIS Summary for Sodium cyanide (PDF 27 pp, 243 K) Toxicological Review for Sodium cyanide (PDF 153 pp, 905 K)  Yes
Reproductive
None
331 Sodium diethyldithiocarbamate 148-18-5 19870131Jan-31-1987 IRIS Summary for Sodium diethyldithiocarbamate (PDF 7 pp, 89 K)  Not Available  Yes
None
None
332 Strontium 7440-24-6 19921001Oct-01-1992 IRIS Summary for Strontium (PDF 11 pp, 114 K)  Not Available  Yes
Musculoskeletal
None
333 Styrene 100-42-5 19921101Nov-01-1992 IRIS Summary for Styrene (PDF 26 pp, 169 K)  Not Available  No
Hematologic
Hepatic
Nervous
None
334 Tetrabromodiphenyl ether 40088-47-9 19900801Aug-01-1990 IRIS Summary for Tetrabromodiphenyl ether (PDF 5 pp, 87 K)  Not Available  Yes
None
None
335 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) 5436-43-1 20080630Jun-30-2008 IRIS Summary for 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) (PDF 14 pp, 128 K) Toxicological Review for 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) (PDF 85 pp, 380 K)  No
Nervous
None
336 1,2,4,5-Tetrachlorobenzene 95-94-3 19870131Jan-31-1987 IRIS Summary for 1,2,4,5-Tetrachlorobenzene (PDF 7 pp, 90 K)  Not Available  Yes
Urinary
None
337 Tetrachlorocyclopentadiene 695-77-2 19900301Mar-01-1990 IRIS Summary for Tetrachlorocyclopentadiene (PDF 6 pp, 83 K)  Not Available  No
None
None
338 2,3,7,8-Tetrachlorodibenzo-p-dioxin 1746-01-6 20120217Feb-17-2012 IRIS Summary for 2,3,7,8-Tetrachlorodibenzo-p-dioxin (PDF 16 pp, 150 K)  Not Available 2,3,7,8-Tetrachlorodibenzo-p-dioxin Support Documents  No
Developmental
Endocrine
Reproductive
None
339 1,1,1,2-Tetrachloroethane 630-20-6 19890301Mar-01-1989 IRIS Summary for 1,1,1,2-Tetrachloroethane (PDF 13 pp, 117 K)  Not Available  No
Hepatic
Urinary
Hepatic
340 1,1,2,2-Tetrachloroethane 79-34-5 20100930Sep-30-2010 IRIS Summary for 1,1,2,2-Tetrachloroethane (PDF 29 pp, 250 K) Toxicological Review for 1,1,2,2-Tetrachloroethane (PDF 153 pp, 907 K)  Yes
Hepatic
Hepatic
341 Tetrachloroethylene 127-18-4 20120210Feb-10-2012 IRIS Summary for Tetrachloroethylene (PDF 38 pp, 0.35 M) Toxicological Review for Tetrachloroethylene (PDF 1,077 pp, 144.20 M)
Tetrachloroethylene Support Documents
 No
Nervous
Ocular
Hepatic
342 2,3,4,6-Tetrachlorophenol 58-90-2 19880301Mar-01-1988 IRIS Summary for 2,3,4,6-Tetrachlorophenol (PDF 8 pp, 93 K)  Not Available  Yes
Hepatic
None
343 Tetraethyl lead 78-00-2 19870131Jan-31-1987 IRIS Summary for Tetraethyl lead (PDF 6 pp, 85 K)  Not Available  Yes
Hepatic
Immune
None
344 Tetraethyldithiopyrophosphate 3689-24-5 19880907Sep-07-1988 IRIS Summary for Tetraethyldithiopyrophosphate (PDF 6 pp, 86 K)  Not Available  Yes
Nervous
None
345 1,1,1,2-Tetrafluoroethane 811-97-2 19950801Aug-01-1995 IRIS Summary for 1,1,1,2-Tetrafluoroethane (PDF 13 pp, 121 K)  Not Available  Yes
Reproductive
None
346 Tetrahydrofuran 109-99-9 20120221Feb-21-2012 IRIS Summary for Tetrahydrofuran (PDF 26 pp, 0.24 M) Toxicological Review for Tetrahydrofuran (PDF 207 pp, 1.22 M)  No
Developmental
Hepatic
Nervous
None
347 Thallium (I), soluble salts Various 20090930Sep-30-2009 IRIS Summary for Thallium (I), soluble salts (PDF 17 pp, 0.14 M) Toxicological Review for Thallium (I), soluble salts (PDF 165 pp, 1.00 M)  No
None
None
348 Thallium acetate 563-68-8 20090930Sep-30-2009 IRIS Summary for Thallium acetate (PDF 17 pp, 0.14 M) Toxicological Review for Thallium acetate (PDF 165 pp, 1.00 M)  Yes
None
None
349 Thallium carbonate 6533-73-9 20090930Sep-30-2009 IRIS Summary for Thallium carbonate (PDF 17 pp, 0.14 M) Toxicological Review for Thallium carbonate (PDF 165 pp, 1.00 M)  Yes
None
None
350 Thallium chloride 7791-12-0 20090930Sep-30-2009 IRIS Summary for Thallium chloride (PDF 17 pp, 0.14 M) Toxicological Review for Thallium chloride (PDF 165 pp, 1.00 M)  Yes
None
None
351 Thallium nitrate 10102-45-1 20090930Sep-30-2009 IRIS Summary for Thallium nitrate (PDF 17 pp, 0.14 M) Toxicological Review for Thallium nitrate (PDF 165 pp, 1.00 M)  Yes
None
None
352 Thallium oxide 1314-32-5 20090930Sep-30-2009 IRIS Summary for Thallium oxide (PDF 16 pp, 0.18 M) Toxicological Review for Thallium oxide (PDF 165 pp, 1.00 M)  Yes
None
None
353 Thallium selenite 12039-52-0 20090930Sep-30-2009 IRIS Summary for Thallium selenite (PDF 15 pp, 0.13 M) Toxicological Review for Thallium selenite (PDF 165 pp, 1.00 M)  Yes
None
None
354 Thallium(I) sulfate 7446-18-6 20090930Sep-30-2009 IRIS Summary for Thallium(I) sulfate (PDF 17 pp, 0.14 M) Toxicological Review for Thallium(I) sulfate (PDF 165 pp, 1.00 M)  Yes
None
None
355 Toluene 108-88-3 20050923Sep-23-2005 IRIS Summary for Toluene (PDF 35 pp, 0.23 M) Toxicological Review for Toluene (PDF 179 pp, 1.80 M)  No
Nervous
Urinary
None
356 2,4-/2,6-Toluene diisocyanate mixture (TDI) 26471-62-5 19950901Sep-01-1995 IRIS Summary for 2,4-/2,6-Toluene diisocyanate mixture (TDI) (PDF 25 pp, 172 K)  Not Available  Yes
Respiratory
None
357 Toxaphene 8001-35-2 19880822Aug-22-1988 IRIS Summary for Toxaphene (PDF 9 pp, 97 K)  Not Available  Yes
None
Hepatic
358 1,2,4-Tribromobenzene 615-54-3 19870331Mar-31-1987 IRIS Summary for 1,2,4-Tribromobenzene (PDF 6 pp, 85 K)  Not Available  No
Hepatic
None
359 Tribromochloromethane 594-15-0 19910301Mar-01-1991 IRIS Summary for Tribromochloromethane (PDF 5 pp, 87 K)  Not Available  No
None
None
360 Tribromodiphenyl ether 49690-94-0 19900801Aug-01-1990 IRIS Summary for Tribromodiphenyl ether (PDF 5 pp, 87 K)  Not Available  Yes
None
None
361 1,1,2-Trichloro-1,2,2-trifluoroethane (CFC-113) 76-13-1 19870406Apr-06-1987 IRIS Summary for 1,1,2-Trichloro-1,2,2-trifluoroethane (CFC-113) (PDF 7 pp, 90 K)  Not Available  Yes
Nervous
None
362 Trichloroacetic acid 76-03-9 20110930Sep-30-2011 IRIS Summary for Trichloroacetic acid (PDF 26 pp, 0.27 M) Toxicological Review for Trichloroacetic acid (PDF 270 pp, 2.08 M)  Yes
Hepatic
Hepatic
363 1,2,4-Trichlorobenzene 120-82-1 19920501May-01-1992 IRIS Summary for 1,2,4-Trichlorobenzene (PDF 14 pp, 118 K)  Not Available  Yes
Endocrine
None
364 Trichlorocyclopentadiene 77323-84-3 19900301Mar-01-1990 IRIS Summary for Trichlorocyclopentadiene (PDF 5 pp, 81 K)  Not Available  No
None
None
365 1,1,1-Trichloroethane 71-55-6 20070928Sep-28-2007 IRIS Summary for 1,1,1-Trichloroethane (PDF 55 pp, 0.39 M) Toxicological Review for 1,1,1-Trichloroethane (PDF 237 pp, 1.08 M)  Yes
Hepatic
Nervous
None
366 1,1,2-Trichloroethane 79-00-5 19880926Sep-26-1988 IRIS Summary for 1,1,2-Trichloroethane (PDF 13 pp, 115 K)  Not Available  Yes
Hematologic
Immune
Hepatic
367 Trichloroethylene 79-01-6 20110928Sep-28-2011 IRIS Summary for Trichloroethylene (PDF 63 pp, 520 K)  Not Available Trichloroethylene Support Documents  No
Developmental
Immune
Hematologic
Hepatic
Urinary
368 Trichlorofluoromethane 75-69-4 19870131Jan-31-1987 IRIS Summary for Trichlorofluoromethane (PDF 7 pp, 89 K)  Not Available  Yes
Cardiovascular
Respiratory
None
369 2,4,5-Trichlorophenol 95-95-4 19910701Jul-01-1991 IRIS Summary for 2,4,5-Trichlorophenol (PDF 7 pp, 90 K)  Not Available  Yes
Hepatic
Urinary
None
370 2,4,6-Trichlorophenol 88-06-2 19910701Jul-01-1991 IRIS Summary for 2,4,6-Trichlorophenol (PDF 13 pp, 115 K)  Not Available  Yes
None
Hematologic
371 2(2,4,5-Trichlorophenoxy) propionic acid (2,4,5-TP) 93-72-1 19880907Sep-07-1988 IRIS Summary for 2(2,4,5-Trichlorophenoxy) propionic acid (2,4,5-TP) (PDF 10 pp, 103 K)  Not Available  Yes
Hepatic
None
372 2,4,5-Trichlorophenoxyacetic acid (2,4,5-T) 93-76-5 19880907Sep-07-1988 IRIS Summary for 2,4,5-Trichlorophenoxyacetic acid (2,4,5-T) (PDF 8 pp, 95 K)  Not Available  Yes
Urinary
None
373 1,1,2-Trichloropropane 598-77-6 19880926Sep-26-1988 IRIS Summary for 1,1,2-Trichloropropane (PDF 6 pp, 86 K)  Not Available  No
Endocrine
Hepatic
Urinary
None
374 1,2,3-Trichloropropane 96-18-4 20090930Sep-30-2009 IRIS Summary for 1,2,3-Trichloropropane (PDF 33 pp, 0.28 M) Toxicological Review for 1,2,3-Trichloropropane (PDF 247 pp, 1.91 M)  Yes
Hepatic
Respiratory
Gastrointestinal
Hepatic
Ocular
Reproductive
375 Tridiphane 58138-08-2 19870131Jan-31-1987 IRIS Summary for Tridiphane (PDF 7 pp, 89 K)  Not Available  Yes
Reproductive
None
376 Triethylamine 121-44-8 19910401Apr-01-1991 IRIS Summary for Triethylamine (PDF 10 pp, 112 K)  Not Available  Yes
Respiratory
None
377 Triethylene glycol monobutyl ether 143-22-6 19940901Sep-01-1994 IRIS Summary for Triethylene glycol monobutyl ether (PDF 6 pp, 93 K)  Not Available  No
None
None
378 Triethylene glycol monoethyl ether 112-50-5 19940901Sep-01-1994 IRIS Summary for Triethylene glycol monoethyl ether (PDF 6 pp, 94 K)  Not Available  No
None
None
379 1,2,3-Trimethylbenzene 526-73-8 20160909Sep-09-2016 IRIS Summary for 1,2,3-Trimethylbenzene (PDF 10 pp, 0.32 M) Toxicological Review for 1,2,3-Trimethylbenzene (PDF 150 pp, 2.65 M)
1,2,3-Trimethylbenzene Support Documents
 No
Hematologic
Nervous
Respiratory
None
380 1,2,4-Trimethylbenzene 95-63-6 20160909Sep-09-2016 IRIS Summary for 1,2,4-Trimethylbenzene (PDF 10 pp, 0.32 M) Toxicological Review for 1,2,4-Trimethylbenzene (PDF 150 pp, 2.65 M)
1,2,4-Trimethylbenzene Support Documents
 No
Developmental
Hematologic
Nervous
Respiratory
None
381 1,3,5-Trimethylbenzene 108-67-8 20160909Sep-09-2016 IRIS Summary for 1,3,5-Trimethylbenzene (PDF 10 pp, 0.32 M) Toxicological Review for 1,3,5-Trimethylbenzene (PDF 150 pp, 2.65 M)
1,3,5-Trimethylbenzene Support Documents
 No
Developmental
Nervous
None
382 2,2,4-Trimethylpentane 540-84-1 20070731Jul-31-2007 IRIS Summary for 2,2,4-Trimethylpentane (PDF 12 pp, 170 K) Toxicological Review for 2,2,4-Trimethylpentane (PDF 43 pp, 312 K)  Yes
None
None
383 1,3,5-Trinitrobenzene 99-35-4 19971001Oct-01-1997 IRIS Summary for 1,3,5-Trinitrobenzene (PDF 10 pp, 99 K)  Not Available 1,3,5-Trinitrobenzene Support Documents  Yes
Hematologic
None
384 2,4,6-Trinitrotoluene (TNT) 118-96-7 19890601Jun-01-1989 IRIS Summary for 2,4,6-Trinitrotoluene (TNT) (PDF 14 pp, 118 K)  Not Available  Yes
Hepatic
Urinary
385 Uranium, natural 7440-61-1 19890101Jan-01-1989 IRIS Summary for Uranium, natural (PDF 4 pp, 77 K)  Not Available  No
None
None
386 Uranium, soluble salts 19891001Oct-01-1989 IRIS Summary for Uranium, soluble salts (PDF 8 pp, 92 K)  Not Available  Yes
Urinary
None
387 Urea 57-13-6 20110713Jul-13-2011 IRIS Summary for Urea (PDF 14 pp, 125 K) Toxicological Review for Urea (PDF 97 pp, 596 K)  No
None
None
388 Vanadium pentoxide 1314-62-1 19880630Jun-30-1988 IRIS Summary for Vanadium pentoxide (PDF 7 pp, 88 K)  Not Available Vanadium pentoxide Support Documents  Yes
Dermal
None
389 Vernam 1929-77-7 19870331Mar-31-1987 IRIS Summary for Vernam (PDF 6 pp, 87 K)  Not Available  No
None
None
390 Vinyl acetate 108-05-4 19901001Oct-01-1990 IRIS Summary for Vinyl acetate (PDF 12 pp, 119 K)  Not Available  No
Nervous
Respiratory
None
391 Vinyl bromide 593-60-2 19930501May-01-1993 IRIS Summary for Vinyl bromide (PDF 11 pp, 108 K)  Not Available  Yes
Hepatic
None
392 Vinyl chloride 75-01-4 20000807Aug-07-2000 IRIS Summary for Vinyl chloride (PDF 64 pp, 0.34 M) Toxicological Review for Vinyl chloride (PDF 197 pp, 1.20 M)  Yes
Hepatic
Hepatic
393 White phosphorus 7723-14-0 19901201Dec-01-1990 IRIS Summary for White phosphorus (PDF 12 pp, 111 K)  Not Available  Yes
Dermal
Reproductive
None
394 Xylenes 1330-20-7 20030221Feb-21-2003 IRIS Summary for Xylenes (PDF 33 pp, 203 K) Toxicological Review for Xylenes (PDF 113 pp, 498 K)  No
Nervous
None
395 Zinc and Compounds 7440-66-6 20050803Aug-03-2005 IRIS Summary for Zinc and Compounds (PDF 21 pp, 154 K) Toxicological Review for Zinc and Compounds (PDF 83 pp, 520 K)  No
Hematologic
Immune
None
396 Zinc cyanide 557-21-1 19870131Jan-31-1987 IRIS Summary for Zinc cyanide (PDF 8 pp, 101 K)  Not Available  Yes
Endocrine
Nervous
None
397 Zineb 12122-67-7 19870331Mar-31-1987 IRIS Summary for Zineb (PDF 8 pp, 93 K)  Not Available  Yes
Endocrine
None