Pyrene

CASRN 129-00-0

  • Status: Pyrene is not being reassessed by IRIS at this time.

Health Hazard Assessments for Effects Other than Cancer


Reference Dose for Oral Exposure (RfD) (PDF) (0 pp, 0 K) last updated: 09/01/1990

RfD (mg/kg-day) System Basis PoD Composite UF Confidence
3 x10-2 Urinary Kidney effects (renal tubular pathology, decreased kidney weights) NOAEL : 7.5 x101
mg/kg-day
3000 Low

Reference Concentration for Inhalation Exposure (RfC) (PDF) (0 pp, 0 K)
Not assessed under the IRIS Program.

Cancer Assessment


Weight of Evidence for Cancer (PDF) (0 pp, 0 K) last updated: 09/01/1990

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (US EPA, 1986)
Basis:
  • Based on no human data and inadequate data from animal bioassays.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (0 pp, 0 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (0 pp, 0 K)

Not assessed under the IRIS Program.

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