IRIS

1,2-Dichlorobenzene

CASRN 95-50-1

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (11 pp, 106 K) last updated: 08/01/1989

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
None 9 x 10-2 No adverse effects observed NOAEL : 8.57 x 101
mg/kg-day
1000 Low

 


Reference Concentration for Inhalation Exposure (RfC) (PDF) (11 pp, 106 K)
Not assessed under the IRIS Program.

 

Cancer Assessment

Weight of Evidence for Cancer (PDF) (11 pp, 106 K) last updated: 11/01/1990

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (US EPA, 1986)
Basis:
  • Based on no human data and evidence of both negative and positive trends for carcinogenic responses in rats and mice.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (11 pp, 106 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (11 pp, 106 K)

Not assessed under the IRIS Program.

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