Nitroguanidine

CASRN 556-88-7

  • IRIS Summary (PDF) (11 pp, 107 K)
  • Status: Nitroguanidine is not being reassessed by IRIS at this time.

Health Hazard Assessments for Effects Other than Cancer


Reference Dose for Oral Exposure (RfD) (PDF) (11 pp, 107 K) last updated: 09/01/1989

RfD (mg/kg-day) System Basis PoD Composite UF Confidence
1 x10-1 Developmental, Other Reduced weight gain in female rats, maternal/ fetal toxicity in rats, and equivocal evidence of developmental toxicity in rabbits NOAEL : 3.16 x102
mg/kg-day
3000 Medium

Reference Concentration for Inhalation Exposure (RfC) (PDF) (11 pp, 107 K)
Not assessed under the IRIS Program.

Cancer Assessment


Weight of Evidence for Cancer (PDF) (11 pp, 107 K) last updated: 09/01/1990

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (US EPA, 1986)
Basis:
  • Pertinent data regarding carcinogenicity have not been located in the available literature.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (11 pp, 107 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (11 pp, 107 K)

Not assessed under the IRIS Program.

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