Chlorobenzene

CASRN 108-90-7

  • IRIS Summary (PDF) (13 pp, 114 K)
  • Status: Chlorobenzene is not being reassessed by IRIS at this time.

Health Hazard Assessments for Effects Other than Cancer


Reference Dose for Oral Exposure (RfD) (PDF) (13 pp, 114 K) last updated: 08/01/1989

RfD (mg/kg-day) System Basis PoD Composite UF Confidence
2 x10-2 Hepatic Histopathologic changes in liver NOAEL : 1.9 x101
mg/kg-day
1000 Medium

Reference Concentration for Inhalation Exposure (RfC) (PDF) (13 pp, 114 K)
Not assessed under the IRIS Program.

Cancer Assessment


Weight of Evidence for Cancer (PDF) (13 pp, 114 K) last updated: 11/01/1990

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (US EPA, 1986)
Basis:
  • No human data, inadequate animal data and predominantly negative genetic toxicity data in bacterial, yeast, and mouse lymphoma cells.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (13 pp, 114 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (13 pp, 114 K)

Not assessed under the IRIS Program.

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