Coke oven emissions

CASRN NA

  • IRIS Summary (PDF) (13 pp, 114 K)
  • Status: Coke oven emissions is not being reassessed by IRIS at this time.

Health Hazard Assessments for Effects Other than Cancer


Reference Dose for Oral Exposure (RfD) (PDF) (13 pp, 114 K)
Not assessed under the IRIS Program.

Reference Concentration for Inhalation Exposure (RfC) (PDF) (13 pp, 114 K)
Not assessed under the IRIS Program.

Cancer Assessment


Weight of Evidence for Cancer (PDF) (13 pp, 114 K) last updated: 05/01/1989

WOE Characterization Framework for WOE Characterization
A (Human carcinogen) Guidelines for Carcinogen Risk Assessment (US EPA, 1986)
Basis:
  • Studies of coke oven workers have shown increased risk of mortality from cancer of the lung, trachea and bronchus; cancer of the kidney; cancer of the prostate; and cancer at all sites combined. In animals, extracts and condensates of coke oven emissions were found to be carcinogenic in both inhalation studies and skin-painting bioassays. The mutagenicity of whole extracts and condensates, as well as their individual components, provides supportive evidence for carcinogenicity.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (13 pp, 114 K)

Not Assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (13 pp, 114 K)

Inhalation Unit Risk: 6.2 x10 -4 per µg/m3
Extrapolation Method: Linearized multistage procedure
Tumor site(s): Respiratory
Tumor type(s): Respiratory cancer (Mazumdar et al., 1975; Land, 1976)


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