IRIS

Allyl chloride

CASRN 107-05-1

Health Hazard Assessments for Effects Other than Cancer

Reference Dose for Oral Exposure (RfD) (PDF) (13 pp, 139 K)
Not assessed under the IRIS Program.

 


Reference Concentration for Inhalation Exposure (RfC) (PDF) (13 pp, 139 K) last updated: 12/01/1991

System RfC (mg/m3) Basis PoD Composite UF Confidence
Nervous 1 x 10-3 Functional and histological peripheral neurotoxicity NOAEL (HEC): 3.6
mg/m3
3000 Low

 

Cancer Assessment

Weight of Evidence for Cancer (PDF) (13 pp, 139 K) last updated: 09/01/1990

WOE Characterization Framework for WOE Characterization
C (Possible human carcinogen) Guidelines for Carcinogen Risk Assessment (US EPA, 1986)
Basis:
  • Classification is based on a low (but biologically important) incidence of forestomach tumors in female mice and positive results in a variety of genetic toxicity tests. Allyl chloride is an alkylating agent and structurally related to probable human carcinogens.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (13 pp, 139 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (13 pp, 139 K)

Not assessed under the IRIS Program.

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