Manganese

CASRN 7439-96-5

  • IRIS Summary (PDF) (48 pp, 265 K)
  • Status: Manganese is not being reassessed by IRIS at this time.

Health Hazard Assessments for Effects Other than Cancer


Reference Dose for Oral Exposure (RfD) (PDF) (48 pp, 265 K) last updated: 11/01/1995

RfD (mg/kg-day) System Basis PoD Composite UF Confidence
1.4 x10-1 Nervous CNS effects NOAEL : 1.4 x10-1
mg/kg-day
1 Medium

Reference Concentration for Inhalation Exposure (RfC) (PDF) (48 pp, 265 K) last updated: 12/01/1993

RfC (mg/m3) System Basis PoD Composite UF Confidence
5 x10-5 Nervous Impairment of neurobehavioral function LOAEL (HEC): 5 x10-2
mg/m3
1000 Medium

Cancer Assessment


Weight of Evidence for Cancer (PDF) (48 pp, 265 K) last updated: 09/26/1988

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (US EPA, 1986)
Basis:
  • Existing studies are inadequate to assess the carcinogenicity of manganese.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (48 pp, 265 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (48 pp, 265 K)

Not assessed under the IRIS Program.

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