Creosote

CASRN 8001-58-9

  • IRIS Summary (PDF) (8 pp, 92 K)
  • Status: Creosote is not being reassessed by IRIS at this time.

Health Hazard Assessments for Effects Other than Cancer


Reference Dose for Oral Exposure (RfD) (PDF) (8 pp, 92 K)
Not assessed under the IRIS Program.

Reference Concentration for Inhalation Exposure (RfC) (PDF) (8 pp, 92 K)
Not assessed under the IRIS Program.

Cancer Assessment


Weight of Evidence for Cancer (PDF) (8 pp, 92 K) last updated: 09/07/1988

WOE Characterization Framework for WOE Characterization
B1 (Probable human carcinogen - based on limited evidence of carcinogenicity in humans) Guidelines for Carcinogen Risk Assessment (US EPA, 1986)
Basis:
  • Limited evidence of the association between occupational creosote contact and subsequent tumor formation, sufficient evidence of local and distant tumor formation after dermal application to mice, and some evidence of mutagenic activity, as well as the well-documented carcinogenicity of other coal tar products to humans.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (8 pp, 92 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (8 pp, 92 K)

Not assessed under the IRIS Program.

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