Fomesafen

CASRN 72178-02-0

Notice - This site contains archived material

  • Status: The IRIS Assessment for the pesticide Fomesafen has been archived and is not being reassessed by IRIS at this time.
  • Archived IRIS Summary (PDF) (8 pp, 95 K)

Information from EPA's Pesticide Program


Additional toxicity information is available from EPA's Pesticide Program, including the following:

Health Hazard Assessments for Effects Other than Cancer


This data is archived and for historical reference only. Please refer to the Pesticide Program Toxicity Value.

Reference Dose for Oral Exposure (RfD) (PDF) (8 pp, 95 K) archived on: 07/15/2016
Not assessed under the IRIS Program.

Reference Concentration for Inhalation Exposure (RfC) (PDF) (8 pp, 95 K) archived on: 07/15/2016
Not assessed under the IRIS Program.

Cancer Assessment


Weight of Evidence for Cancer (PDF) (8 pp, 95 K) archived on: 07/15/2016

WOE Characterization Framework for WOE Characterization
C (Possible human carcinogen) Guidelines for Carcinogen Risk Assessment (US EPA, 1986)
Basis:
  • Fomesafen produced liver adenomas and carcinomas in both sexes of Charles River CD-1 mice.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (8 pp, 95 K)

Oral Slope Factor: 1.9 x10 -1 per mg/kg-day
Drinking Water Unit Risk: 5.4 x10 -6 per µg/L
Extrapolation Method: Linearized multistage procedure, extra risk
Tumor site(s): Hepatic
Tumor type(s): Liver adenomas and carcinomas (Huntingdon, 1985)


Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (8 pp, 95 K)

Not Assessed under the IRIS Program.

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