Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX)
CASRN 2691-41-0 | DTXSID3024237
- IRIS Summary (PDF) (11 pp, 107 K)
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF) (11 pp, 107 K)
Last Updated: 09/26/1988
| System | RfD (mg/kg-day) | Basis | PoD | Composite UF | Confidence |
|---|---|---|---|---|---|
| Hepatic | 5 x 10-2 | Hepatic lesions |
NOAEL
: 5.0 x 101 mg/kg-day |
1000 | Low |
Reference Concentration for Inhalation Exposure (RfC) (PDF) (11 pp, 107 K)
Not assessed under the IRIS Program.
Cancer Assessment
Weight of Evidence for Cancer (PDF) (11 pp, 107 K)
Last Updated: 03/01/1989
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| D (Not classifiable as to human carcinogenicity) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- No cancer bioassays or epidemiological studies are available.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (11 pp, 107 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (11 pp, 107 K)
Not assessed under the IRIS Program.
Additional EPA toxicity information may be available by visiting the following sites:
- Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
- Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
- Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.
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Critical Effect Systems
Chemical Structure for
Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX)
