Butyl benzyl phthalate

CASRN 85-68-7

Health Hazard Assessments for Effects Other than Cancer


Reference Dose for Oral Exposure (RfD) (PDF) (12 pp, 111 K) last updated: 09/01/1989

RfD (mg/kg-day) System Basis PoD Composite UF Confidence
2 x10-1 Hepatic Significantly increased liver-to-body weight and liver-to-brain weight ratios NOAEL : 1.59 x102
mg/kg-day
1000 Low

Reference Concentration for Inhalation Exposure (RfC) (PDF) (12 pp, 111 K)
Not assessed under the IRIS Program.

Cancer Assessment


Weight of Evidence for Cancer (PDF) (12 pp, 111 K) last updated: 08/22/1988

WOE Characterization Framework for WOE Characterization
C (Possible human carcinogen) Guidelines for Carcinogen Risk Assessment (US EPA, 1986)
Basis:
  • Based on statistically significant increase in mononuclear cell leukemia in female rats; the response in male rats was inconclusive and there was no such response in mice.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (12 pp, 111 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (12 pp, 111 K)

Not assessed under the IRIS Program.


Butyl benzyl phthalate is being reassessed.

Assessment Manager(s): Teneille Walker (walker.teneille@epa.gov), Andrew Hotchkiss (hotchkiss.andrew@epa.gov)

Step Assessment Materials Released to the Public Release Date Public Meeting Date
1 Problem Formulation Materials N/A N/A
1 Preliminary Assessment Materials 09/2014 02/2015
4 Public Comment Draft TBD TBD
4 Peer Review Draft TBD TBD
7 Post Final Assessment TBD

Please note: Any future dates displayed under Release Date are estimates and subject to change.

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