Paraquat

CASRN 1910-42-5

Health Hazard Assessments for Effects Other than Cancer


Reference Dose for Oral Exposure (RfD) (PDF) (12 pp, 107 K) last updated: 03/31/1987

RfD (mg/kg-day) System Basis PoD Composite UF Confidence
4.5 x10-3 Respiratory Chronic pneumonitis NOEL : 4.5 x10-1
mg/kg-day
100 High

Reference Concentration for Inhalation Exposure (RfC) (PDF) (12 pp, 107 K)
Not assessed under the IRIS Program.

Cancer Assessment


Weight of Evidence for Cancer (PDF) (12 pp, 107 K) last updated: 08/22/1988

WOE Characterization Framework for WOE Characterization
C (Possible human carcinogen) Guidelines for Carcinogen Risk Assessment (US EPA, 1986)
Basis:
  • Paraquat produced squamous cell carcinoma, an uncommon tumor, in the head region in both sexes of Fischer 344 rats.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (12 pp, 107 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (12 pp, 107 K)

Not assessed under the IRIS Program.

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