IRIS

Paraquat

CASRN 1910-42-5

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (12 pp, 107 K) last updated: 03/31/1987

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Respiratory 4.5 x 10-3 Chronic pneumonitis NOEL : 4.5 x 10-1
mg/kg-day
100 High

 


Reference Concentration for Inhalation Exposure (RfC) (PDF) (12 pp, 107 K)
Not assessed under the IRIS Program.

 

Cancer Assessment

Weight of Evidence for Cancer (PDF) (12 pp, 107 K) last updated: 08/22/1988

WOE Characterization Framework for WOE Characterization
C (Possible human carcinogen) Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)
Basis:
  • Paraquat produced squamous cell carcinoma, an uncommon tumor, in the head region in both sexes of Fischer 344 rats.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (12 pp, 107 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (12 pp, 107 K)

Not assessed under the IRIS Program.

Additional EPA toxicity information may be available by visiting the following sites, including the following:
  • Human Health Benchmarks for Pesticides (HHBP) information. The HHBP website provides toxicity reference values for a number of pesticides to help determine if there is a potential health risk when pesticides are detected in water. However, the toxicity information from the HHBP table may be useful for other purposes.
  • EPA Pesticide Program toxicity information. This link provides information from EPA's Pesticide Program on the derivation of toxicity reference values.
  • EPA's Chemistry Dashboard. This link provides information from EPA's National Center for Computational Toxicology (NCCT) on chemical structures, experimental and predicted physicochemical and toxicity data, and additional links to relevant websites and applications.
  • Contact us about pesticides

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