n-Butanol
CASRN 71-36-3 | DTXSID1021740
- IRIS Summary (PDF) (10 pp, 100 K)
- Status: Development of the n-butanol (re)assessment has been discontinued.
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF) (10 pp, 100 K)
Last Updated: 03/31/1987
| System | RfD (mg/kg-day) | Basis | PoD | Composite UF | Confidence |
|---|---|---|---|---|---|
| Nervous | 1 x 10-1 | Hypoactivity and ataxia |
NOAEL
: 1.25 x 102 mg/kg-day |
1000 | Low |
Reference Concentration for Inhalation Exposure (RfC) (PDF) (10 pp, 100 K)
Not assessed under the IRIS Program.
Cancer Assessment
Weight of Evidence for Cancer (PDF) (10 pp, 100 K)
Last Updated: 03/01/1991
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| D (Not classifiable as to human carcinogenicity) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- Based on no human and no animal cancer data.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (10 pp, 100 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (10 pp, 100 K)
Not assessed under the IRIS Program.
- Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
- Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
- Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.
Note: The n-butanol (re)assessment has been discontinued. A new/updated assessment will not be added to the IRIS database at this time.
Assessment Manager(s): Andrew Kraft (kraft.andrew@epa.gov), Dahnish Shams (shams.dahnish@epa.gov)
| Step | Assessment Materials Released to the Public | Release Date | Public Meeting Date |
|---|---|---|---|
| 4 | Peer Review Draft | 09/2011 | N/A |
| Discontinued | 12/2018 |
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Critical Effect Systems
Chemical Structure for
n-Butanol
