IRIS

n-Butanol

CASRN 71-36-3

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (10 pp, 100 K) last updated: 03/31/1987

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Nervous 1 x 10-1 Hypoactivity and ataxia NOAEL : 1.25 x 102
mg/kg-day
1000 Low

 


Reference Concentration for Inhalation Exposure (RfC) (PDF) (10 pp, 100 K)
Not assessed under the IRIS Program.

 

Cancer Assessment

Weight of Evidence for Cancer (PDF) (10 pp, 100 K) last updated: 03/01/1991

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (US EPA, 1986)
Basis:
  • Based on no human and no animal cancer data.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (10 pp, 100 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (10 pp, 100 K)

Not assessed under the IRIS Program.


n-Butanol is being reassessed.

Assessment Manager(s): Deborah Segal (segal.deborah@epa.gov)

Step Assessment Materials Released to the Public Release Date Public Meeting Date
1 Problem Formulation Materials N/A N/A
1 Preliminary Assessment Materials N/A N/A
4 Public Comment Draft TBD TBD
4 Peer Review Draft TBD TBD
7 Post Final Assessment TBD

Please note: Any future dates displayed under Release Date are estimates and subject to change.

You will need Adobe Reader to view some of the files on this page. See EPA’s PDF page to learn more.

Quick Check