Bromobenzene

CASRN 108-86-1

Health Hazard Assessments for Effects Other than Cancer


Reference Dose for Oral Exposure (RfD) (PDF) (27 pp, 243 K) last updated: 09/30/2009

RfD (mg/kg-day) System Basis PoD Composite UF Confidence
8 x10-3
(Chronic)
Hepatic Hepatocellular cytomegaly in male B6C3F1 mice BMDL10 : 24.1
mg/kg-day
3000 Low/Medium
2 x10-2
(Subchronic)
Hepatic Hepatocellular cytomegaly in male B6C3F1 mice BMDL10 : 24.1
mg/kg-day
1000 Medium

Reference Concentration for Inhalation Exposure (RfC) (PDF) (27 pp, 243 K) last updated: 09/30/2009

RfC (mg/m3) System Basis PoD Composite UF Confidence
6 x10-2
(Chronic)
Hepatic Hepatocellular cytomegaly in female B6C3F1 mice BMCL10 : 63
mg/m3
1000 Low/Medium
2 x10-1
(Subchronic)
Hepatic Hepatocellular cytomegaly in female B6C3F1 mice BMCL10 (HEC): 63
mg/m3
300 Medium

Cancer Assessment


Weight of Evidence for Cancer (PDF) (27 pp, 243 K) last updated: 09/30/2009

WOE Characterization Framework for WOE Characterization
Inadequate information to assess carcinogenic potential Guidelines for Carcinogen Risk Assessment (US EPA, 2005)
Basis:
  • Under the Guidelines for Carcinogen Risk Assessment (U.S. EPA, 2005a), there is "inadequate information to assess the carcinogenic potential" of bromobenzene.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (27 pp, 243 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (27 pp, 243 K)

Not assessed under the IRIS Program.

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