IRIS

2-Methylnaphthalene

CASRN 91-57-6

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (21 pp, 158 K) last updated: 12/22/2003

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Respiratory 4 x 10-3 Pulmonary alveolar proteinosis BMD05 : 4.7
mg/kg-day
1000 Low

 


Reference Concentration for Inhalation Exposure (RfC) (PDF) (21 pp, 158 K) last updated: 12/22/2003
Information reviewed but value not estimated.

 

Cancer Assessment

Weight of Evidence for Cancer (PDF) (21 pp, 158 K) last updated: 12/22/2003

WOE Characterization Framework for WOE Characterization
Data are inadequate for an assessment of human carcinogenic potential Revised Draft Guidelines for Carcinogen Risk Assessment (US EPA, 1999)
Basis:
  • Under the draft revised guidelines for carcinogen risk assessment (U.S. EPA, 1999), EPA concludes the data are inadequate for an assessment of human carcinogenic potential of 2-methylnaphthalene. Based on the absence of data concerning the carcinogenic potential of 2-methylnaphthalene in humans and limited equivocal evidence in animals.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (21 pp, 158 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (21 pp, 158 K)

Not assessed under the IRIS Program.

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