CASRN 30560-19-1

Notice - This site contains archived material

  • Status: The IRIS Assessment for the pesticide Acephate has been archived and is not being reassessed by IRIS at this time.
  • Archived IRIS Summary (PDF) (13 pp, 114 K)
  • Archive Disclaimer: The IRIS Program has archived a number of IRIS entries for pesticides that have been assessed more recently by EPA's Pesticide Program. The IRIS program announced in 2004 that chemicals that are solely used as pesticides would not be re-assessed.

Information from EPA's Pesticide Program

Additional toxicity information is available from EPA's Pesticide Program, including the following:

This data is archived and for historical reference only. Please refer to the Pesticide Program Toxicity Value.

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (13 pp, 114 K) archived on: 07/15/2016

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Nervous 4 x 10-3 Inhibition of brain ChE LEL : 1.2 x 10-1
30 High


Reference Concentration for Inhalation Exposure (RfC) (PDF) (13 pp, 114 K)
Not assessed under the IRIS Program.


Cancer Assessment

Weight of Evidence for Cancer (PDF) (13 pp, 114 K) archived on: 07/15/2016

WOE Characterization Framework for WOE Characterization
C (Possible human carcinogen) Guidelines for Carcinogen Risk Assessment (US EPA, 1986)
  • The classification is based on increased incidence of hepatocellular carcinomas and adenomas in female mice.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (13 pp, 114 K)

Oral Slope Factor: 8.7 x10 -3 per mg/kg-day
Drinking Water Unit Risk: 2.5 x10 -7 per µg/L
Extrapolation Method: Linearized multistage procedure, extra risk
Tumor site(s): Hepatic
Tumor type(s): Liver adenomas and carcinomas (Chevron Chemical, 1982a)

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (13 pp, 114 K)

Not Assessed under the IRIS Program.

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