IRIS

Paraquat

CASRN 1910-42-5

  • IRIS Summary (PDF) (12 pp, 107 K)
  • Status: EPA announced in a 2004 Federal Register Notice that chemicals used as pesticides would not be re-assessed by the IRIS Program. This entry in the IRIS database is preserved at the request of EPA program and regional offices. Additional toxicological information may be found under "Other EPA Information."

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (12 pp, 107 K) Last Updated: 03/31/1987

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Respiratory 4.5 x 10-3 Chronic pneumonitis NOEL : 4.5 x 10-1
mg/kg-day
100 High

 


Reference Concentration for Inhalation Exposure (RfC) (PDF) (12 pp, 107 K)
Not assessed under the IRIS Program.

 

Cancer Assessment

Weight of Evidence for Cancer (PDF) (12 pp, 107 K) Last Updated: 08/22/1988

WOE Characterization Framework for WOE Characterization
C (Possible human carcinogen) Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)
Basis:
  • Paraquat produced squamous cell carcinoma, an uncommon tumor, in the head region in both sexes of Fischer 344 rats.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (12 pp, 107 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (12 pp, 107 K)

Not assessed under the IRIS Program.

Additional EPA toxicity information may be available by visiting the following sites:

You will need Adobe Reader to view some of the files on this page. See EPA’s PDF page to learn more.