IRIS

n-Butanol

CASRN 71-36-3

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (10 pp, 100 K) Last Updated: 03/31/1987

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Nervous 1 x 10-1 Hypoactivity and ataxia NOAEL : 1.25 x 102
mg/kg-day
1000 Low

 


Reference Concentration for Inhalation Exposure (RfC) (PDF) (10 pp, 100 K)
Not assessed under the IRIS Program.

 

Cancer Assessment

Weight of Evidence for Cancer (PDF) (10 pp, 100 K) Last Updated: 03/01/1991

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)
Basis:
  • Based on no human and no animal cancer data.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (10 pp, 100 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (10 pp, 100 K)

Not assessed under the IRIS Program.


Note: The n-butanol (re)assessment has been discontinued. A new/updated assessment will not be added to the IRIS database at this time.

Assessment Manager(s): James Avery (avery.james@epa.gov)

Step Assessment Materials Released to the Public Release Date Public Meeting Date
4 Peer Review Draft 09/2011 N/A
  Discontinued 12/2018  

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