IRIS

Chlorite (sodium salt)

CASRN 7758-19-2 | DTXSID8021272

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (19 pp, 143 K) Last Updated: 10/12/2000

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Nervous, Developmental 3 x 10 -2 Neurodevelopmental effects NOAEL : 3
mg/kg-day
100 Medium/High

 


Reference Concentration for Inhalation Exposure (RfC) (PDF) (19 pp, 143 K) Last Updated: 10/12/2000
Information reviewed but value not estimated.

 

Cancer Assessment

Weight of Evidence for Cancer (PDF) (19 pp, 143 K) Last Updated: 10/12/2000

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)
Carcinogenic potential cannot be determined Proposed Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1996)
Basis:
  • Under the current guidelines (U.S. EPA, 1986), chlorite is classified as Group D; not classifiable as to human carcinogenicity because of inadequate data in humans and animals. Under the draft Carcinogen Assessment Guidelines (U.S. EPA, 1996), the human carcinogenicity of chlorite cannot be determined because of a lack of human data and limitations in animal studies.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (19 pp, 143 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (19 pp, 143 K)

Not assessed under the IRIS Program.


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