Methylphenol CASRN 106-44-5 | IRIS

IRIS

Reference Dose for Oral Exposure (RfD) (PDF) (13 pp, 114 K) Last Updated: 08/01/1991
Information reviewed but value not estimated.

Reference Concentration for Inhalation Exposure (RfC) (PDF) (13 pp, 114 K) Last Updated: 04/01/1992
Information reviewed but value not estimated.

Weight of Evidence for Cancer (PDF) (13 pp, 114 K) Last Updated: 09/01/1990

WOE Characterization	Framework for WOE Characterization
C (Possible human carcinogen)	Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)

Basis:

Based on an increased incidence of skin papillomas in mice in an initiation-promotion study. The three cresol isomers produced positive results in genetic toxicity studies both alone and in combination.
This may be a synopsis of the full weight-of-evidence narrative.

Not assessed under the IRIS Program.

Not assessed under the IRIS Program.

Additional EPA toxicity information may be available by visiting the following sites:

Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

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