GENE EXPRESSION IN PRE-IMPLANTATION MAMMALIAN EMBRYOS
Notice - This site contains archived material(s)
Archive disclaimer
Archive
disclaimer
Archived files are provided for reference
purposes only. These files are no longer maintained by the Agency and may be outdated. For
current EPA information, go to www.epa.gov. It is EPA's policy to
support reasonable accommodation to persons with disabilities, pursuant to the Rehabilitation
Act of 1973, 29 U.S.C. 791. If you need assistance with accessing archived files, contact
EPA's Reasonable Accommodations
or submit a request using the Contact Us form.
Abstract
The pre-implantation mammalian embryo is initially under the control of maternal informational macromolecules that are accumulated during oogenesis. ubsequently, the genetic program of development becomes dependent upon new transcription derived from activation of the embryonic genome. everal embryonic transcripts including those that encode growth factors, cell junction components and plasma membrane ion transporters are required for normal progression of the embryo to the blastocyst stage. he pattern of genes expressed and the overall program of development is subject to the influences of genomic imprinting as well as external influences encountered by the embryo within the maternal reproductive tract.
Citation
Schultz, G. AND S. Heyner. GENE EXPRESSION IN PRE-IMPLANTATION MAMMALIAN EMBRYOS. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-93/171.
Additional Information
Mutation Research 296(1/2):17-31, 1992