ECOTOX Knowledgebase
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Aquatic life, terrestrial plants and wildlife The ECOTOXicology Knowledgebase (ECOTOX) is a comprehensive, publicly available Knowledgebase providing single chemical environmental toxicity data on aquatic life, terrestrial plants and wildlife.

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Disclaimer: You should consult the original scientific paper to ensure an understanding of the context of the data retrieved from ECOTOX.

Getting Started

  • Use Search if you know exact parameters or search terms (chemical, species, etc.)
  • Use Explore to see what data may be available in ECOTOX (including data plots)

Other Links


Download the entire database as an ASCII file via the button below.

New Additions!

In addition to chemical data updates, ECOTOX has added new features based on user feedback:

  1. Cyanotoxins is now a 'Chemical Group' that you can use to query or filter results in SEARCH and EXPLORE. Studies on toxicity of cyanotoxins are being incorporated on an on-going basis, with the currently included results available at [ Cyanotoxins ].
  2. Duration was recently added as a filter parameter that you can apply in both SEARCH and EXPLORE queries. You can use this filter to limit the results returned to a specific value or range for the Observed Duration, in days. [The Observed Duration is the time at which an effect measurement was observed/measured and reported (for example, a 24-hour LC50).]
  3. The 'Custom Group' option in EXPLORE by Effects was recently expanded to include the full definitions in 'Browse Effect Measurements', with description, synonyms, and gene/protein symbols (as relevant). Now you can type and select Effect Measurements to create custom groups on-the-fly without needing to cross reference the Terms Appendix (Appendix S).

Did you know? ECOTOX includes 'Custom Group' options in EXPLORE to create custom groups with chemicals, species, or effect measurements for summary and visualization of available data records. For example, you can create a custom group for chemicals of interest by using the 'Browse Chemicals' option to type in and select from the list of chemicals currently verified in ECOTOX OR by entering a list of CAS numbers into the 'Enter by CAS Number' option.

Search Tip

Using Custom Group and Custom Plots

The following is an example how you can use the Custom Group and Custom Plot options to explore and visualize available data.

  1. Select "Chemicals", Icon for Chemicals, from the Explore page.
  2. Select "Create Custom Group" (upper left of page).
  3. button that says Create Custom Group
  4. Browse Chemicals by typing name of chemical of interest in open box and selecting those of interest (hold down Ctrl to select multiples).
  5. Select "Explore Data", button that says Explore Data (bottom right of "Create Custom Group" box).
  6. The Group Summary output table will have chemicals from the selection that have test results extracted to ECOTOX, with the list of chemicals and associated records in the table. You can also select "Records" at the top of the screen to view the records.
  7. Group Summary, Records, and Plot View buttons with Group Summary selected
  8. To view data in a Custom Plot, select "Plot View" Group Summary, Records, and Plot buttons with Plot View selected, and then "Custom" (above the plot).
  9. Effect x Chem, Dur x Chem, Dur x Endpt, and Custom buttons with Custom selected
  10. Select "Change Plot Parameters" Change Plot Parameters... (below the Custom button) and select desired options. The Y-axis can be set to the continuous variables of Concentration or Duration. The X-axis and Legend can be set to categorical variables, including Chemical, Species, Effect, Endpoint, or group.

Literature Search Dates

Targeted literature searches are conducted using chemical names, synonyms, and CASRNs in multiple search engines (e.g., Web of Science, Agricola, ToxNet, ProQuest, etc). Chemicals listed below had targeted searches corresponding to the date indicated in the second column. Each search is identified in the table by the requested chemical or chemical group, with some searches including multiple chemicals/CASRNs. Citations from these searches are reviewed. Studies meeting inclusionary criteria added to ECOTOX; toxicity data results may take 6 months or longer to appear on-line. There may be more recent publications in ECOTOX for a chemical due to related chemical literature searches.


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