ECOTOX Knowledgebase

About ECOTOXAquatic life, terrestrial plants and wildlife

ECOTOX is a comprehensive Knowledgebase providing single chemical environmental toxicity data on aquatic and terrestrial species.
Read more in: Olker et al. 2022

Learn More

Getting Started

  • Use Search if you know exact parameters or search terms (chemical, species, etc.)
  • Use Explore to see what data may be available in ECOTOX (including data plots)

Other Links

ECOTOX-related documentation and resources.

New Additions!

The latest updates to the ECOTOX Knowledgebase.

Search Tip

Example usage of ECOTOX Knowledgebase

ASCII Download

Download the entire database as an ASCII file via the button below.

Literature Search Dates

Targeted literature searches are conducted using chemical names, synonyms, and CASRNs in multiple search engines (e.g., Web of Science, Agricola, ToxNet, ProQuest, etc). Chemicals listed below had targeted searches corresponding to the date indicated in the fourth column. Each search is identified in the table by the requested chemical or chemical group, with some searches including multiple chemicals/CASRNs.

Citations from these searches will undergo data abstraction if the studies meet the inclusionary criteria for ECOTOX. Toxicity data results may take 6 months or longer to appear on-line. There may be more recent publications in ECOTOX for a chemical due to related chemical literature searches.

 

New Additions!

In addition to chemical data updates, ECOTOX has added new features based on user feedback:

  1. NEW option in Explore to export Plot View data file and information to use R (https://www.r-project.org/) to create customizable, high-quality figures comparable to display on Plot View tab. This option is designed for users with basic knowledge of R with R installed. The R script can be customized by the user (i.e., change plot layout/colors).
    • In Explore, select module of interest (Chemicals, Species, Effects, or Publications) and then select group(s) or Create Custom Group(s). Click 'Explore Data'.
    • Within Explore Module, apply Query Filters of interest (in left hand panel).
    • Navigate to the Plot View (3rd tab on the top).
    • The default plot type is 'Custom', where this new option allows the user to export the data and R script to re-create the plots viewed on Explore.
    • Within plot type Custom click 'Change Plot Parameters' to select different options for x-axis, y-axis, and legend category (if desired).
    • Click green 'Export' button and select 'Data to R Plot'.
    • Save .zip file to preferred directory and folder. File will be date and time stamped with name 'ecotox_R_YYYY-MM-DD-HHMMSS.zip' and include comma delimited data file (ecotox_explore_data_YYYY-MM-DD-HHMMSS.csv) and text file with R script (ecotox_explore_data_ YYYY-MM-DD-HHMMSS.r).
    • Unzip files to a common folder. Open and run R script (file ending in ".r") in R or RStudio.
    • R script will install required packages (if needed), import data file, and create color and greyscale figures (exported as .jpeg files) with selections from Explore for x-axis, y-axis, and legend category. Note that text labels will be suppressed when there are more than 50 categories for the x-axis or legend category.

    As with the Plot View in Explore, records are plotted if they can be converted to Standardized Concentration Units (unit ratio equivalent to ppm) – see ECOTOX Help for information on ECOTOX unit conversion logic. Records are ordered by Concentration (low-high), with display and export limited to a maximum of 3,000 records.

  2. The NEW Explore Publications module continues to be improved to provide options to query by citation information (author, title, ECOREF Number, DOI) and display toxicity data by reference. This new explore module follows the general structure and options within the other Explore modules (for Chemicals, Species, and Effects), but also has some functionality that differs (such as, how the records are displayed) - these continue to be tested and may be incorporated into the Chemical, Species, and Effects Explore modules in the future. We welcome feedback and ideas! Please send comments through the Contact Us page.

Did you know? There are multiple resources on how to use ECOTOX, including:

  • The new ECOTOX Knowledgebase Virtual Training recording and slide deck (presented in May 2022) that are now available on the EPA's new New Approach Methods (NAMs) Training website. This training website includes resources for multiple tools. To find the most recent ECOTOX trainings, filter the Topic and Subtopic to 'Ecotoxicology' and sort by Year.
  • Looking for short videos to get started using the ECOTOX Knowledgebase? Check out the ECOTOX Tool Tips videos on Navigating the Application, Help Page, Explore Module, Data Visualization, Searching ECOTOX, and Exporting ECOTOX Data.
  • Help page which includes the ECOTOX User Guide, Learning the Basics, Data Field Definitions and Terms, and the Terms Appendix with the ECOTOX-specific controlled vocabulary.
  • Contact Us page where you can submit comments and questions about ECOTOX including technical questions about conducting queries and exporting data.

Search Tip

Using Duration Filter in SEARCH

Duration was recently added as a filter parameter that you can apply in both SEARCH and EXPLORE queries to limit the results returned to a specific value or range for the Observed Duration, in days. [The Observed Duration is the time at which an effect measurement was observed/measured and reported (for example, a 24-hour LC50).]

The following is an example how you can apply the Duration filter in SEARCH.

  1. From SEARCH, expand "All Test Conditions", Test Conditions sidebar menu, on the left-hand side under "Parameters".
  2. Scroll to the bottom of the expanded "All Test Conditions" section to find the options under "Specify Duration (Observed)".
  3. Search filters to specify duration
  4. Filter results to a specific duration returned by typing the requested duration in days, as a number, in the text box under "Insert specific duration (days)". For example, if you are only interested in 24-hour LC50s, type 1 under "Insert specific duration (days)", The value one day is set in the duration filter., and then also go to the "All Endpoints", Endpoints sidebar menu, section under "Parameters" to select "LC50" Endpoint LC 50 is selected..
  5. Then select the green "Update Search" button, Update Search button, on the bottom left-hand side to apply filters and view resulting records.
  6. If you are instead interested in a range for duration, enter the minimum, maximum, or both minimum and maximum under "Enter range for duration (days)".
  7. Duration range search filter.
  8. The results table will include the records that meet the parameters you selected and/or entered within Chemical, Species, Effects, Endpoints, Test Conditions, and Publication Options windows under "Parameters" in SEARCH.
  9. You can restore the default selections across all parameters by clicking on the "Reset All" button Reset All button, or within a single window by clicking on the "Reset" button in top right of a window Reset button.
  10. In the results table, the Obs. Dur. (Days) column will reflect the Duration filter you applied. To include additional data fields such as the Author Reported Observed Duration in the displayed and exported table, select "Customize Output Fields" Customize output fields button and select from the list of available fields.

Get Updates via Email

Submit your info below to receive notifications when quarterly updates are available.

Please correct the following errors:

    Contact Us to ask a question, provide feedback, or report a problem.