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CELLULAR, BIOCHEMICAL, AND MOLECULAR TECHNIQUES IN DEVELOPMENTAL TOXICOLOGY
Citation:
Abbott, B D., M B. Rosen, AND G A. Held. CELLULAR, BIOCHEMICAL, AND MOLECULAR TECHNIQUES IN DEVELOPMENTAL TOXICOLOGY. Chapter 14, Ron Hood (ed.), Developmental and Reproductive Toxicology, A Practical Approach. CRC Press LLC, Boca Raton, FL, (2004).
Description:
Cellular, molecular and biochemical approaches vastly expand the possibilities for revealing the underlying mechanisms of developmental toxicity. The increasing interest in embryonic development as a model system for the study of gene expression has resulted in a cornucopia of information and approaches available to the toxicologist. A number of molecular biological techniques are presented in this chapter with examples of examples of applications in developmental biology and toxicology. Although it is beyond the scope of this chapter to provide detailed methods and protocols, several sources of such information are cited.