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EXPOSURE ANALYSIS
Citation:
Maschwitz, D. EXPOSURE ANALYSIS. Proceedings of Pellston Workshop, Montana, 1998.
Description:
This proceedings chapter presents the state of the science regarding the evaluation of exposure as it relates to WQC, SQGs, and wildlife criteria (WC). . . . In summary, the exposure workgroup concluded the following: There should be greater use of mechanistic models to predict bioavailability and chemical effects among different sites as a function of water-quality parameters, the chemical form in water, other water constituents, and the interaction of the contaiminant with the biotic receptor site. Exposure variability should be recognized by deriving chemical-specific averaging periods from kinetic-based toxicity and accumulation models. Uncertainties in developing and applying criteria associated with multipathway exposure should be recognized through limits on tissue residues. Media-specific criteria should be harmonized by coupling existing media-specific models and conducting demonstration projects at well-characterized field sites. A comprehensive, hierarchical understanding of biological responses to pollutants is needed to link chemical exposure to responses of the receptor site, organisms, populations, communities, and ecosystems.