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ASSESSING ECOLOGICAL RISK OF THE ANDROGEN TRENBOLONE IN THE ENVIRONMENT
Citation:
Durhan, E J. ASSESSING ECOLOGICAL RISK OF THE ANDROGEN TRENBOLONE IN THE ENVIRONMENT. Presented at Minnesota Chromatography Forum, Minneapolis, MN, March 16, 2004.
Description:
Endocrine disrupting chemicals in the environment can cause changes in reproductive development and characteristics of fish and other aquatic organisms. Since the early 90s, the effects of environmental estrogens have been seen in waste water treatment plant effluents in Europe and North America. Recently, there have been reports of masculinization of female fathead minnows collected from a site adjacent to a beef feedlot in Nebraska. At our laboratory in Duluth we have evaluated the androgen, trenbolone, a commonly used growth promoter in beef by using a fathead minnow short term reproductive test. In our field work we have measured the occurrence of trenbolone in a beef feedlot discharge and in river water downstream and upstream of the discharge over time. In addition, our laboratory in RTP has evaluated the in vitro androgenic activity of these samples. This data will give us insight to the question: Is the presence of the androgen trenbolone related to androgenic activity found in the environment?