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THE NEUROTOXICANT TRIMETHYLTIN INDUCES APOPTOSIS VIA CASPASE ACTIVATION, P38 PROTEIN KINASE, AND OXIDATIVE STRESS IN PC12 CELLS.

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Citation:

Jenkins, S. AND S Barone. THE NEUROTOXICANT TRIMETHYLTIN INDUCES APOPTOSIS VIA CASPASE ACTIVATION, P38 PROTEIN KINASE, AND OXIDATIVE STRESS IN PC12 CELLS. TOXICOLOGY LETTERS 147:63-72, (2004).

Description:

This manuscript describes in vitro cell signaling mechanisms involved in trimethyltin-induced neurotoxicity. The signaling pathways and effects presage effects on developmental process including neural differentiation and apoptosis. These mechanisms may be pertinent to other organotins.

Record Details:

Record Type:DOCUMENT( JOURNAL/ PEER REVIEWED JOURNAL)
Product Published Date:01/05/2004
Record Last Revised:12/22/2005
Record ID: 75853