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CHROMATOGRAPHIC AND MASS SPECTRAL STUDIES OF PERFLUOROOCTANESULFONATE AND THREE PERFLUOROOCTANESULFONAMIDES
Citation:
Kuehl, D W. AND B. V. Rozynov. CHROMATOGRAPHIC AND MASS SPECTRAL STUDIES OF PERFLUOROOCTANESULFONATE AND THREE PERFLUOROOCTANESULFONAMIDES. RAPID COMMUNICATION IN MASS SPECTROMETRY. John Wiley & Sons, Ltd., Chichester, Uk, 17(2003):2364-2369, (2003).
Description:
The chromatographic and mass spectral characteristics of perfluorooctanesulfonate (PFOS) and three nitrogen-substituted perfluorooctanesulfonamides have been obtained. A methyl/phenol mixed phase fused silica capillary column was used for GC analysis, while a C18 reversed phase microbore column was used for LC analyses. MS and MS/MS spectra were generated using EI, argon CE, methane positive and negative ion CI, and ES ionization modes. MS/MS spectra of the amides showed ions characteristic of both the fluorinated hydrocarbon and the sulfonamide portion of the molecules. The fragmentation pathway was studied using hydrogen/deuterium exchange, and was thought to involve a cyclic intermediate ion. Formation of molecular weight information was only partially successful. Negative ion ES/MS spectra provided intense anions for the amides, and an anion for PFOS from which molecular weight information could be obtained, while ES/MS/MS produced product ions that could be used to detect the presence of these compounds in biological or environmental samples.