You are here:
MITOCHONDRIAL OXIDANT PRODUCTION BY POLLUTANT DUST AND NO-MEDIATED APOPTOSIS IN HUMAN ALVEOLAR MACHROPHAGE
Citation:
Huang, YuhChin T, J M. Soukup, S. Harder, AND S E. Becker. MITOCHONDRIAL OXIDANT PRODUCTION BY POLLUTANT DUST AND NO-MEDIATED APOPTOSIS IN HUMAN ALVEOLAR MACHROPHAGE. American Journal of Physiology - Lung Cellular and Molecular Physiology 284:C24-C32, (2002).
Description:
Residual oil fly ash (ROFA) is a pollutant dust that stimulates production of reactive oxygen species (ROS) from mitochondria and apoptosis in alveolar macrophages (AM), but the relationship between these two processes is unclear. In this study, human AM were incubated with ROFA or vanadyl sulfate (VOSO4), the major metal constituent in ROFA, with or without nitro-L-arginine methyl ester (L-NAME), diphenyleneiodonium (DPI), and mitochondrial electron transport inhibitors.
Record Details:
Record Type:DOCUMENT( JOURNAL/ PEER REVIEWED JOURNAL)
Product Published Date:09/11/2002
Record Last Revised:12/22/2005
Record ID:
65814