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CD14-DEPENDENT AIRWAY NEUTROPHIL RESPONSE TO INHALED LPS: ROLE OF ATOPY
Citation:
Eldridge, M. W., M. P. Reed, D. P. Peden, AND P A. Bromberg. CD14-DEPENDENT AIRWAY NEUTROPHIL RESPONSE TO INHALED LPS: ROLE OF ATOPY. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 107:31-35, (2001).
Description:
Background: Inhaled endotoxin (LPS) is associated with airway neutrophilic (PMN) inflammation in both asthmatic and control subjects, with asthmatic subjects demonstrating possibly higher sensitivity. CD14 is the principal receptor mediating LPS responses in vivo. It is unkown whether constiutive CD14 can predict the magnitude of the PMN response after LPS inhalation and whether atopy plays a role in this response.
Record Details:
Record Type:DOCUMENT( JOURNAL/ PEER REVIEWED JOURNAL)
Product Published Date:01/01/2001
Record Last Revised:12/22/2005
Record ID:
65638