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AN OVERVIEW OF THE USE OF QSARS FOR RANKING AND PRIORITIZING LARGE CHEMICAL INVENTORIES FOR ENVIRONMENTAL RISK ASSESSMENT
Citation:
Russom, C L., R. L. BRETON, J. D. Walker, AND S P. Bradbury. AN OVERVIEW OF THE USE OF QSARS FOR RANKING AND PRIORITIZING LARGE CHEMICAL INVENTORIES FOR ENVIRONMENTAL RISK ASSESSMENT. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 22(8):1810-1821, (2003).
Description:
Ecological risk assessments for chemical stressors are used to establish linkages between likely exposure concentrations and adverse effects to ecological receptors. At times, it is useful to conduct screening risk assessments to assist in prioritizing or ranking chemicals on the basis of potential hazard and exposure assessment parameters. Ranking of large chemical inventories can provide evidence for focusing research and/or cleanup efforts on specific chemicals of concern. Because of financial and time constraints, data gaps exist, and the risk assessor is left with decisions on which models to use to estimate the parameter of concern . . . The ranking methods described include those related to current regulatory issues associated with chemical inventories from Canada, Europe, and the United States and an example of a screening-level risk assessment conducted on chemicals associated with a watershed in the midwest region of the United States.