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HYDROLOGIC CONDITIONS AFFECTING THE TROPOSPHERIC FLUX OF VINCLOZOLIN AND ITS DEGRADATION PRODUCTS
Citation:
Vallero, D A. AND J. J. Peirce. HYDROLOGIC CONDITIONS AFFECTING THE TROPOSPHERIC FLUX OF VINCLOZOLIN AND ITS DEGRADATION PRODUCTS. HYDROLOGICAL SCIENCE AND TECHNOLOGY 17(1-4):371-385, (2001).
Impact/Purpose:
1) Develop methods of ecological exposure (e.g. rapid , sensitive analytical screening methods for a select list of antibiotics widely used in agriculture primarily in CAFOs (confined animal feeding operations).
2) Do Measurements & Provide data for multicompartment models of fate and transport.
3) Study biomagnification of specific chemicals and toxic metals.
4) Study specific pharmaceuticals:
*Determine the routes of entry and the impact of environmental factors such as rainfall on the movement and survivorability of selected antimicrobials in the environment.
*Determine if the entry of agriculture based antibiotics into the environment contributes to resistance in bacterial populations.
*Determine the contribution from municipal waste water treatment plants to antibiotic loading in the environment.
5) Develop methods for the analysis of alkylphenol ethoxylates and derivatives.
Description:
A laboratory chamber was used to determine hydrologic conditions that lead to the tropospheric flux of a suspected anti-androgenic dicarboximide fungicide, vinclozolin (3-(3,5-dichlorophenyl)-5-methyl-5-vinyl-oxzoli-dine-2,4-dione) and three degradation products from sterilized and unsterilized North Carolina Piedmont aquic hapludult soils following fungicide spray applications. Fluid-filled pore space, fluid pH, and fungicide incorporation into the soil were studied. Results indicate that the formation of the metabolite, 2-[(3,5-dichlorophenyl)-carbamoyl]oxy-2-methyl-3-butenoic acid ("M1-butenoic acid"), occurs from base-catalyzed hydrolysis, but the degradation is enhanced by the presence of microbes. M1-butenoic acid flux was also found to increase with lower pH levels in the soil pore fluid and when the fungicide was incorporated into the soil. Reduction and acid-catalytic reactions also appear to play a role in dicarboximide degradation in the soil at lower pore fluid pH levels.
This work has been funded in part by the EPA. It has been subjected to Agency review and approved for publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.