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TRANS-O-HYDROXYBENZYLIDENEPYRUVATE HYDRATASE-ALDOLASE AS BIOCATALYST
Citation:
Eaton, R W. TRANS-O-HYDROXYBENZYLIDENEPYRUVATE HYDRATASE-ALDOLASE AS BIOCATALYST. APPLIED AND ENVIRONMENTAL MICROBIOLOGY 66(6):2668-2672, (1999).
Description:
The hydratase-aldolase-catalyzed conversion of trans-o-hydroxybenzylidenepyruvate to salicylaldehyde and pyruvate is an intermediate reaction in the conversion of naphthalene to salicylate by bacteria. Here, a variety of aromatic aldehydes and some non-aromatic aldehydes together with pyruvate have been shown to be substrates for aldol condensations catalyzed by this enzyme in extracts of the recombinant strain Escherichia coli JM109(pRE701). Some of the products of these reactions were also compared as substrates in the opposite (hydration-aldol cleavage) reaction.
Record Details:
Record Type:DOCUMENT( JOURNAL/ PEER REVIEWED JOURNAL)
Product Published Date:06/06/2000
Record Last Revised:12/22/2005
Record ID:
65119