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COMPARISON OF FOUR HUMAN STUDIES OF PERINATAL EXPOSURE TO METHYLMERCURY FOR USE IN RISK ASSESSMENT
Citation:
Cicmanec*, J L. COMPARISON OF FOUR HUMAN STUDIES OF PERINATAL EXPOSURE TO METHYLMERCURY FOR USE IN RISK ASSESSMENT. Wallace, K. (ed.), TOXICOLOGY. Elsevier Science BV, Amsterdam, Netherlands, 111:157-162, (1996).
Description:
Newer data from human epidemiologic studies of methylmercury (MeHg) poisoning in which perinatal exposure occurred are available from four distinct populations. The results of an Iraqi grain-consuming population are compared to results from studies performed in fish-consuming groups in the Faroe Islands, the Seychelles Islands and in Peruvian fishing villages. A comparison of the results indicate that the Iraqi population does not represent a sensitive subpopulation within a perinatal group, but rather the relative lower threshold identified from this study ws the result of confounders. Use of this benchmark dose for regulatory purposes may place a severe limitation upon fish consumption in the US that is not fully supported by the scientific data.