Citation:

Patonay, T., R S. Varma*, A. Vass, A. Levai, AND J. Dudas. HIGHLY DIASTEREOSELECTIVE MICHAEL ADDITION OF FLAVANONE TO ITS CHALCONE PRECURSOR UNDER SOLVENT-FREE CONDITIONS USING MICROWAVES. International Conference on Microwave Chemistry; Proceedings, Antibes, Frances, 9/4-7/00.

Description:

Substituted 2'-hydroxychalcones were found to give an equilibrium mixture of the starting chalcone and the corresponding flavanone in 4:6 - 1:3 ratio in the presence of various supports and MW irradiation. MW irradiation of 2'-hydroxychalcones in the presence of DBU gave two hitherto unknown diasteromeric dimers in a highly diastereoselective Michael addition of the carbanion of flavanone to the chalcones. Trimeric products have also been isolated in some cases.

Record Details:

Record Type:DOCUMENT( PRESENTATION/ PAPER)

Product Published Date:09/01/2000

Record Last Revised:06/21/2006

Record ID: 63537

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Related Organizations:

Role :OWNER

Organization Name :US ENVIRONMENTAL PROTECTION AGENCY

Organization Name :OFFICE OF RESEARCH AND DEVELOPMENT

Organization Name :NATIONAL RISK MANAGEMENT RESEARCH LABORATORY

Organization Name :SUSTAINABLE TECHNOLOGY DIVISION

Document IDs:

EPA Number :EPA/600/A-01/012