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EFFECT OF THREE DIFFERENT SIZED FRACTIONS OF OUTDOOR PM ON INFLAMMATORY AND OXIDATIVE MARKERS IN VIVO
Citation:
Dick, C. A., P. Singh, P A. Evansky, S. Becker, AND M I. Gilmour. EFFECT OF THREE DIFFERENT SIZED FRACTIONS OF OUTDOOR PM ON INFLAMMATORY AND OXIDATIVE MARKERS IN VIVO. Presented at American Thoracic Society, Atlanta, GA, May 17-22, 2002.
Description:
EFFECT OF THREE DIFFERENT SIZED FRACTIONS OF OUTDOOR PM ON INFLAMMATORY MARKERS IN VIVO
C A J Dick', P Singh2, P. Evansky3, S Becker3 and M I Gilmour3.
'Center For Environmental Medicine and Lung Biology, UNC, Chapel Hill, NC 27599 2NCSU, Raleigh, NC 'Experimental Toxicology Division, NHEERL, RTP, NC 27711
Epidemiological studies have shown that a rise in PM10 is associated with exacerbations of respiratory disease and increased mortality. The mechanism of lung injury after exposure to particulate air pollution is unknown, but has been thought to be mediated by particles of smaller diameter and oxidants generated at their surface. Particulate matter from Research Triangle Park (NC) was collected into 3 different fractions, coarse (CR) (>3.5.tm), fine (Fl) (1.7-3.5 m) and fine/ultrafine (FU) (
EPA cooperative agreement CR824915