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MULTIMEDIA CHEMICAL ANALYSIS PLAN FOR CHILDREN'S AGGREGATE EXPOSURE FIELD STUDIES IN NORTH CAROLINA AND OHIO
Citation:
Chuang, J. C., N. Junod, N. K. Wilson, M. C. Brinkman, AND M K. Morgan. MULTIMEDIA CHEMICAL ANALYSIS PLAN FOR CHILDREN'S AGGREGATE EXPOSURE FIELD STUDIES IN NORTH CAROLINA AND OHIO. Presented at International Society of Exposure Analysis 2002 Conference, Vancouver, Canada, August 11-15, 2002.
Impact/Purpose:
The overall objectives of CTEPP were to measure the aggregate exposures of approximately 260 preschool children and their adult caregivers to low levels of a suite of pesticides and organic pollutants that the children may encounter in their everyday environments, and to apportion the routes of exposure and estimate the relative contributions of each route.
Description:
The samples collected in the CTEPP North Carolina and Ohio field campaigns were analyzed for a suite of organic chemicals in various compound classes, chosen because of their possible carcinogenicity, acute or chronic toxicity, or potential for endocrine system disruption. The targeted compound classes include acid herbicides, carbamates, chlorinated phenols, hydroxy-polycyclic aromatic hydrocarbons (OH-PAHs), organochlorine (OC) pesticides, organophosphate (OP) pesticides, PAHs, polychlorinated biphenyls (PCBs), phthalate esters (PHs), alkylphenols, pyrethroid pesticides, and triazines. Analytical methods for the chemical characterization of these compounds were based on methods developed previously in small-scale pilot studies. A cost-effective approach was established for the sample analysis effort. This approach divided the compound classes into two groups: neutral/moderately polar (carbamates, OC and OP pesticides, PAHs, PCBs, PHs, pyrethroids, triazine, and alkylphenols) and polar (acid herbicides, OH-PAHs, and chlorinated phenols). Because of cost constraints, we consolidated the moderately polar compounds with the neutral compounds into a single group. Different sample extraction and cleanup methods were used for the neutral/moderately polar and the acid groups. Within each group, different extraction/cleanup methods were required for the various sample matrices of interest. The sample matrices included air, dust, soil, dermal wipe, surface wipe, food, drinking water, and urine. For the neutral/moderately polar group, the sample extract had to be analyzed twice to cover all the target chemicals. The polar group required two derivatization methods (methylation and silylation) and two (GC/MS) analysis runs. A total of 30 standard operating procedures were generated to describe the various chemical analysis methods.
This work has been funded wholly or in part by the United States Environmental Protection Agency under contract No. 68-D-99-011 to Battelle. It has been subjected to Agency review and approved for publication.