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WINCADRE (COMPUTER-AIDED DATA REVIEW AND EVALUATION)
Citation:
Coakley, W. A., L C. Butler, V. D. Dandge, J. R. Caldwell, AND V. D. Desican. WINCADRE (COMPUTER-AIDED DATA REVIEW AND EVALUATION). Presented at PITTCON 2000 Science for the 21st Century, New Orleans, LA, March 11-18, 2000.
Impact/Purpose:
The primary objective of this research is to improve current PM population exposure models to more accurately predict exposures for the general population and susceptible sub-populations. Through model improvements, a better understanding of the major factors controlling exposure to PM will be achieved. Specific objectives of this research are to:
- predict total personal exposure to PM10 and PM2.5 for the general and for susceptible sub-populations residing in different urban environments
- estimate the contribution of ambient PM to predicted total PM exposures
- determine what factors are of primary importance in determining PM exposures, including an analysis of the effects of time spent in various microenvironments and the importance of spatial variability in ambient PM concentrations
- determine what factors contribute the greatest uncertainty to model predictions and make recommendations for measurement and modeling studies to reduce these uncertainties
- predict daily and annual average exposures using single or multi-day time-activity diaries
- incorporate state-of-the-art dosimetric models of the lung into PM population exposure and dose models
- evaluate models against measured data from PM panel and other exposure measurement studies
- develop exposure and dose metrics applicable to acute and chronic environmental epidemiology studies
Description:
WinCADRE (Computer-Aided Data Review and Evaluation) is a Windows -based program designed for computer-assisted data validation. WinCADRE is a powerful tool which significantly decreases data validation turnaround time. The electronic-data-deliverable format has been designed in Excel, a widely-used, user-friendly spreadsheet program. WinCADRE reviews all data and checks laboratory calculations. WinCADRE data-review logic is based on the EPA Contract Laboratory Program (CLP)guidelines for data validation. However, the method, criteria, defects and flags are all customizable by the user for alternate CLP and non-CLP methods. This allows the user to customize method specifications, specify data review criteria, customize defect messages, and specify qualifier-flag assignments. The data are displayed from the file and are consolidated into customized user interface screens for added convenience. Reports are provided for import errors (missing and invalid), data listings [field samples, detection limits, analytical sequence, TIC (tentatively identified compound) results], analysis results (field samples, matrix spikes, post-digest spikes, duplicates, laboratory control samples, serial dilutions), and data review (data review, intermediate flag results, final flags spreadsheet). All reports may be previewed on-screen, printed as a hard copy, or saved to disk, allowing customization of the report formats.
This abstract has been subjected to Agency review and approved for publication.