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PHYSIOLOGICAL EFFECTS OF TRANSGENERATIONAL CADMIUM EXPOSURE.
Citation:
Foran, C M., B. N. Peterson, AND W H. Benson. PHYSIOLOGICAL EFFECTS OF TRANSGENERATIONAL CADMIUM EXPOSURE. Presented at 21st Annual Meeting of the Society of Environmental Toxicology and Chemistry, Nashville, TN, 12-16 November 2000.
Description:
A series of assays were modified or developed to use with small fish species, specifically Japanese medaka (Oryzias latipes). These assays were used to compare the effects of environmentally relevant cadmium (Cd) exposure on indicators of endocrine function in adult animals previously exposed in ovo or as hatchlings. Adults were raised either from eggs produced during a two week exposure to o, 1, 5, 10 ?g/L Cd or from medaka fry exposed for two weeks beginning 2 days after hatching. Tissue from two animals were combined to determine hepatic vitellogenin (VTG), plasma estradiol and testosterone, hepatic estrogen receptor content, and induction of steroidogenesis following gonadotropin releasing hormone injection. Changes in VTG have not been found to be concentration dependent or reflect changes in reproductive success of adult pairs.