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IRIS Toxicological Review and Summary Documents For 1,1,1-Trichloroethane (External Review Draft)
On April 20, 2007, an external peer-review panel workshop was hosted by an independent contractor on this Toxicological Review Document. Completing this process, a final report of the comments from this workshop were collected and is available from this site.
Citation:
U.S. EPA. IRIS Toxicological Review and Summary Documents For 1,1,1-Trichloroethane (External Review Draft).
Impact/Purpose:
EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 1,1,1-trichloroethane that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and appropriately in derivation of the dose-response assessments and toxicological characterization.
Description:
EPA has conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 1,1,1-trichloroethane that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and appropriately in derivation of the dose-response assessments and toxicological characterization.
URLs/Downloads:
Toxicological Review of 1,1,1-Trichloroethane (External Review Draft) (PDF, 200 pp, 1764 KB, about PDF)Charge to External Peer Reviewers (PDF, 4 pp, 21 KB, about PDF)
FINAL REPORT FOR PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING OF 1,1,1-TRICHLOROETHANE (PDF, 187 pp, 2169 KB, about PDF)
IRIS TOXICOLOGICAL REVIEW AND SUMMARY DOCUMENTS FOR 1,1,1-TRICHLOROETHANE (PEER REVIEW PLAN)
HEALTH ASSESSMENT DOCUMENT FOR 1,1,1-TRICHLOROETHANE (METHYL CHLOROFORM). FINAL REPORT
FR NOTICE: FEBRUARY 27, 2007
CONSOLIDATED COMMENTS FROM THE EXTERNAL PEER REVIEW (FINAL) (PDF, 31 pp, 251 KB, about PDF)