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DOSE RESPONSE OF ELASTASE-INDUCED EMPHYSEMA IN HAMSTERS
Citation:
Raub, J., R. Mercer, F. Miller, J. Graham, AND J. O'Neil. DOSE RESPONSE OF ELASTASE-INDUCED EMPHYSEMA IN HAMSTERS. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-81/332 (NTIS PB82248048), 1981.
Description:
Elastase-induced emhysema in hamsters was studied using pulmonary function tests in an effort to develop techniques for determining the effects of air pollutants on the progression of this disease. It appears that as little as 6 units of elastase produces mild emphysema in hamsters, which is detectable by pulmonary function testing. Of the tests, the DLCO and N2 slope were the most effective in detecting the degree of impairment.
Record Details:
Record Type:DOCUMENT( REPORT )
Product Published Date:10/26/1981
Record Last Revised:12/22/2005
Record ID:
51236