Science Inventory

IDENTIFICATION OF TWO GLUCURONIDE METABOLITES OF DOXYLAMINE VIA THERMOSPRAY/MASS SPECTROMETRY AND THERMOSPRAY/MASS SPECTROMETRY/MASS SPECTROMETRY

Citation:

Korfmacher, W., C. Holder, L. Betowski, AND R. Mitchum. IDENTIFICATION OF TWO GLUCURONIDE METABOLITES OF DOXYLAMINE VIA THERMOSPRAY/MASS SPECTROMETRY AND THERMOSPRAY/MASS SPECTROMETRY/MASS SPECTROMETRY. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-87/173 (NTIS PB88159751).

Description:

Analysis of a high-pressure liquid chromatography fraction containing two urinary glucuronide metabolites of doxylamine by thermospray mass spectrometry (TSP/MS) provided (MH)+ ions for each metabolite. TSP/MS/MS of the (MH)+ ions provided a fragment ion characteristic of these metabolites. The results demonstrate the utility of TSP/MS analysis for biologically derived glucuronide metabolites. (Copyright (c) Journal of Analytical Toxicology, 1987.)

Record Details:

Record Type:DOCUMENT( REPORT )
Product Published Date:05/24/2002
Record Last Revised:12/10/2002
Record ID: 51070