You are here:
INFLUENCE OF TEMPERATURE DURING THE ELECTRIC AND MAGNETIC FIELD-INDUCED ALTERATION OF CALCIUM RELEASE FROM BRAIN TISSUE, IN VITRO
Citation:
Blackman, C., S. Benane, AND D. House. INFLUENCE OF TEMPERATURE DURING THE ELECTRIC AND MAGNETIC FIELD-INDUCED ALTERATION OF CALCIUM RELEASE FROM BRAIN TISSUE, IN VITRO. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-91/120 (NTIS PB91211433), 1991.
Description:
The release of calcium ions from in vitro preparation of chicken brain-tissue has been used by several investigators to demonstrate the interaction of electric and magnetic (EM) fields with biological systems. or exposures with radiofrequency radiation amplitude modulated at extremely low frequencies (ELF), enhancement of calcium release is always reported, n contrast, when only ELF EM fields are employed, the release of calcium ions has been to be inhibited reported by one research group and to be enhanced by another group. he results in this report demonstrate that either observation, or a null result, it possible under exposure to 16-Hz sinusoidal EM fields, at 14.1 Vrms/m (in air), and 64 nTesla-rms, depending upon the thermal condition of the samples prior to and during exposure. hen the sample temperature is ascending during he 20 minute exposure to a final temperature of either 35, 36, or 37 but not 38 or 39 degrees C, enhanced release is observed; when the temperature is stable during exposure (i.e., within + 0.3 degrees C) to a final value of 36 or 37 but not 35 or 38 degrees C, the release is reduced; and when descending to any final temperature between 35 to 38 degrees C, a null result occurs. his finding may reconcile the disagreement in the direction of the field-induced response and explain why the experimental result has been difficult to replicate in some laboratories. ore importantly, this result also provides a clue to the underlying basis for the field-induced phenomenon.